Response gene to complement 32 suppresses adipose tissue thermogenic genes through inhibiting β3-adrenergic receptor/mTORC1 signaling.
Chen S, Mei X, Yin A, Yin H, Cui XB, Chen SY.
Chen S, et al. Among authors: yin a, yin h.
FASEB J. 2018 Sep;32(9):4836-4847. doi: 10.1096/fj.201701508R. Epub 2018 Mar 26.
FASEB J. 2018.
PMID: 29579398
Free PMC article.
These results indicate that RGC-32 suppresses adipose tissue thermogenic gene expression through down-regulation of beta3-AR expression and mTORC1 activity via a PI3K/Akt-dependent mechanism.-Chen, S., Mei, X., Yin, A., Yin, H., Cui, X.-B., Chen, S.-Y. Respon …
These results indicate that RGC-32 suppresses adipose tissue thermogenic gene expression through down-regulation of beta3-AR expression and …