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Page 1
Kidney resident macrophages have distinct subsets and multifunctional roles.
Chew C, Brand OJ, Yamamura T, Lawless C, Morais MRPT, Zeef L, Lin IH, Howell G, Lui S, Lausecker F, Jagger C, Shaw TN, Krishnan S, McClure FA, Bridgeman H, Wemyss K, Konkel JE, Hussell T, Lennon R. Chew C, et al. Among authors: bridgeman h. Matrix Biol. 2024 Mar;127:23-37. doi: 10.1016/j.matbio.2024.02.002. Epub 2024 Feb 7. Matrix Biol. 2024. PMID: 38331051 Free article.
Amphiregulin-producing γδ T cells are vital for safeguarding oral barrier immune homeostasis.
Krishnan S, Prise IE, Wemyss K, Schenck LP, Bridgeman HM, McClure FA, Zangerle-Murray T, O'Boyle C, Barbera TA, Mahmood F, Bowdish DME, Zaiss DMW, Grainger JR, Konkel JE. Krishnan S, et al. Among authors: bridgeman hm. Proc Natl Acad Sci U S A. 2018 Oct 16;115(42):10738-10743. doi: 10.1073/pnas.1802320115. Epub 2018 Oct 2. Proc Natl Acad Sci U S A. 2018. PMID: 30279177 Free PMC article.
Effect of Modified Vaccinia Ankara-5T4 and Low-Dose Cyclophosphamide on Antitumor Immunity in Metastatic Colorectal Cancer: A Randomized Clinical Trial.
Scurr M, Pembroke T, Bloom A, Roberts D, Thomson A, Smart K, Bridgeman H, Adams R, Brewster A, Jones R, Gwynne S, Blount D, Harrop R, Wright M, Hills R, Gallimore A, Godkin A. Scurr M, et al. Among authors: bridgeman h. JAMA Oncol. 2017 Oct 12;3(10):e172579. doi: 10.1001/jamaoncol.2017.2579. Epub 2017 Oct 12. JAMA Oncol. 2017. PMID: 28880972 Free PMC article. Clinical Trial.
Low-Dose Cyclophosphamide Induces Antitumor T-Cell Responses, which Associate with Survival in Metastatic Colorectal Cancer.
Scurr M, Pembroke T, Bloom A, Roberts D, Thomson A, Smart K, Bridgeman H, Adams R, Brewster A, Jones R, Gwynne S, Blount D, Harrop R, Hills R, Gallimore A, Godkin A. Scurr M, et al. Among authors: bridgeman h. Clin Cancer Res. 2017 Nov 15;23(22):6771-6780. doi: 10.1158/1078-0432.CCR-17-0895. Epub 2017 Aug 29. Clin Cancer Res. 2017. PMID: 28855352 Free PMC article. Clinical Trial.
On-going Mechanical Damage from Mastication Drives Homeostatic Th17 Cell Responses at the Oral Barrier.
Dutzan N, Abusleme L, Bridgeman H, Greenwell-Wild T, Zangerle-Murray T, Fife ME, Bouladoux N, Linley H, Brenchley L, Wemyss K, Calderon G, Hong BY, Break TJ, Bowdish DME, Lionakis MS, Jones SA, Trinchieri G, Diaz PI, Belkaid Y, Konkel JE, Moutsopoulos NM. Dutzan N, et al. Among authors: bridgeman h. Immunity. 2017 Jan 17;46(1):133-147. doi: 10.1016/j.immuni.2016.12.010. Epub 2017 Jan 10. Immunity. 2017. PMID: 28087239 Free PMC article.
Eliminating roles for T-bet and IL-2 but revealing superior activation and proliferation as mechanisms underpinning dominance of regulatory T cells in tumors.
Colbeck EJ, Hindley JP, Smart K, Jones E, Bloom A, Bridgeman H, McPherson RC, Turner DG, Ladell K, Price DA, O'Connor RA, Anderton SM, Godkin AJ, Gallimore AM. Colbeck EJ, et al. Among authors: bridgeman h. Oncotarget. 2015 Sep 22;6(28):24649-59. doi: 10.18632/oncotarget.5584. Oncotarget. 2015. PMID: 26433463 Free PMC article.
Escalating regulation of 5T4-specific IFN-γ+ CD4+ T cells distinguishes colorectal cancer patients from healthy controls and provides a target for in vivo therapy.
Scurr M, Bloom A, Pembroke T, Srinivasan R, Brown C, Smart K, Bridgeman H, Davies M, Hargest R, Phillips S, Christian A, Hockey T, Gallimore A, Godkin A. Scurr M, et al. Among authors: bridgeman h. Cancer Immunol Res. 2013 Dec;1(6):10.1158/2326-6066.CIR-13-0035. doi: 10.1158/2326-6066.CIR-13-0035. Cancer Immunol Res. 2013. PMID: 24409450 Free PMC article.
Progression of carcinogen-induced fibrosarcomas is associated with the accumulation of naïve CD4+ T cells via blood vessels and lymphatics.
Ondondo B, Jones E, Hindley J, Cutting S, Smart K, Bridgeman H, Matthews KK, Ladell K, Price DA, Jackson DG, Godkin A, Ager A, Gallimore A. Ondondo B, et al. Among authors: bridgeman h. Int J Cancer. 2014 May 1;134(9):2156-67. doi: 10.1002/ijc.28556. Epub 2013 Nov 8. Int J Cancer. 2014. PMID: 24142504 Free PMC article.
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