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Vaccines targeting ESR1 activating mutations elicit anti-tumor immune responses and suppress estrogen signaling in therapy resistant ER+ breast cancer.
Dailey GP, Rabiola CA, Lei G, Wei J, Yang XY, Wang T, Liu CX, Gajda M, Hobeika AC, Summers A, Marek RD, Morse MA, Lyerly HK, Crosby EJ, Hartman ZC. Dailey GP, et al. Among authors: hobeika ac. Hum Vaccin Immunother. 2024 Dec 31;20(1):2309693. doi: 10.1080/21645515.2024.2309693. Epub 2024 Feb 8. Hum Vaccin Immunother. 2024. PMID: 38330990 Free PMC article.
Recent developments in therapeutic cancer vaccines.
Morse MA, Chui S, Hobeika A, Lyerly HK, Clay T. Morse MA, et al. Nat Clin Pract Oncol. 2005 Feb;2(2):108-13. doi: 10.1038/ncponc0098. Nat Clin Pract Oncol. 2005. PMID: 16264883 Review.
Increasing vaccine potency through exosome antigen targeting.
Hartman ZC, Wei J, Glass OK, Guo H, Lei G, Yang XY, Osada T, Hobeika A, Delcayre A, Le Pecq JB, Morse MA, Clay TM, Lyerly HK. Hartman ZC, et al. Vaccine. 2011 Nov 21;29(50):9361-7. doi: 10.1016/j.vaccine.2011.09.133. Epub 2011 Oct 12. Vaccine. 2011. PMID: 22001882 Free PMC article.
Polyfunctional anti-human epidermal growth factor receptor 3 (anti-HER3) antibodies induced by HER3 vaccines have multiple mechanisms of antitumor activity against therapy resistant and triple negative breast cancers.
Osada T, Hartman ZC, Wei J, Lei G, Hobeika AC, Gwin WR, Diniz MA, Spector N, Clay TM, Chen W, Morse MA, Lyerly HK. Osada T, et al. Among authors: hobeika ac. Breast Cancer Res. 2018 Aug 9;20(1):90. doi: 10.1186/s13058-018-1023-x. Breast Cancer Res. 2018. PMID: 30092835 Free PMC article.
Vaccine-Induced Memory CD8+ T Cells Provide Clinical Benefit in HER2 Expressing Breast Cancer: A Mouse to Human Translational Study.
Crosby EJ, Gwin W, Blackwell K, Marcom PK, Chang S, Maecker HT, Broadwater G, Hyslop T, Kim S, Rogatko A, Lubkov V, Snyder JC, Osada T, Hobeika AC, Morse MA, Lyerly HK, Hartman ZC. Crosby EJ, et al. Among authors: hobeika ac. Clin Cancer Res. 2019 May 1;25(9):2725-2736. doi: 10.1158/1078-0432.CCR-18-3102. Epub 2019 Jan 11. Clin Cancer Res. 2019. PMID: 30635338 Free PMC article. Clinical Trial.
76 results