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High ionic strength vector formulations enhance gene transfer to airway epithelia.
bioRxiv [Preprint]. 2024 Jan 23:2024.01.22.576687. doi: 10.1101/2024.01.22.576687.
bioRxiv. 2024.
PMID: 38328187
Free PMC article.
Preprint.
Functional correction of CFTR mutations in human airway epithelial cells using adenine base editors.
Krishnamurthy S, Traore S, Cooney AL, Brommel CM, Kulhankova K, Sinn PL, Newby GA, Liu DR, McCray PB.
Krishnamurthy S, et al. Among authors: brommel cm.
Nucleic Acids Res. 2021 Oct 11;49(18):10558-10572. doi: 10.1093/nar/gkab788.
Nucleic Acids Res. 2021.
PMID: 34520545
Free PMC article.
Item in Clipboard
Reciprocal mutations of lung-tropic AAV capsids lead to improved transduction properties.
Cooney AL, Brommel CM, Traore S, Newby GA, Liu DR, McCray PB Jr, Sinn PL.
Cooney AL, et al. Among authors: brommel cm.
Front Genome Ed. 2023 Nov 22;5:1271813. doi: 10.3389/fgeed.2023.1271813. eCollection 2023.
Front Genome Ed. 2023.
PMID: 38077224
Free PMC article.
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Adeno-Associated Virus-Based Gene Therapy for Lifelong Correction of Genetic Disease.
Brommel CM, Cooney AL, Sinn PL.
Brommel CM, et al.
Hum Gene Ther. 2020 Sep;31(17-18):985-995. doi: 10.1089/hum.2020.138. Epub 2020 Aug 21.
Hum Gene Ther. 2020.
PMID: 32718227
Free PMC article.
Review.
Item in Clipboard
Transduction of Pig Small Airway Epithelial Cells and Distal Lung Progenitor Cells by AAV4.
Chen OG, Mather SE, Brommel CM, Hamilton BA, Ehler A, Villacreses R, Girgis RE, Abou Alaiwa M, Stoltz DA, Zabner J, Li X.
Chen OG, et al. Among authors: brommel cm.
Cells. 2021 Apr 25;10(5):1014. doi: 10.3390/cells10051014.
Cells. 2021.
PMID: 33923029
Free PMC article.
Item in Clipboard
V-Type ATPase Mediates Airway Surface Liquid Acidification in Pig Small Airway Epithelial Cells.
Li X, Villacreses R, Thornell IM, Noriega J, Mather S, Brommel CM, Lu L, Zabner A, Ehler A, Meyerholz DK, Stoltz DA, Zabner J.
Li X, et al. Among authors: brommel cm.
Am J Respir Cell Mol Biol. 2021 Aug;65(2):146-156. doi: 10.1165/rcmb.2020-0349OC.
Am J Respir Cell Mol Biol. 2021.
PMID: 33789071
Free PMC article.
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Nominal carbonic anhydrase activity minimizes airway-surface liquid pH changes during breathing.
Thornell IM, Li X, Tang XX, Brommel CM, Karp PH, Welsh MJ, Zabner J.
Thornell IM, et al. Among authors: brommel cm.
Physiol Rep. 2018 Jan;6(2):e13569. doi: 10.14814/phy2.13569.
Physiol Rep. 2018.
PMID: 29380953
Free PMC article.
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