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Deciphering the origin and therapeutic targets of cancer of unknown primary: a case report that illustrates the power of integrative whole-exome and transcriptome sequencing analysis.
Al Assaad M, Shin N, Sigouros M, Manohar J, Antysheva Z, Kotlov N, Kiriy D, Nikitina A, Kleimenov M, Tsareva A, Makarova A, Fomchenkova V, Dubinina J, Boyko A, Almog N, Wilkes D, Escalon JG, Saxena A, Elemento O, Sternberg CN, Nanus DM, Mosquera JM. Al Assaad M, et al. Among authors: nanus dm. Front Oncol. 2024 Jan 22;13:1274163. doi: 10.3389/fonc.2023.1274163. eCollection 2023. Front Oncol. 2024. PMID: 38318324 Free PMC article.
Whole-Exome Sequencing of Metastatic Cancer and Biomarkers of Treatment Response.
Beltran H, Eng K, Mosquera JM, Sigaras A, Romanel A, Rennert H, Kossai M, Pauli C, Faltas B, Fontugne J, Park K, Banfelder J, Prandi D, Madhukar N, Zhang T, Padilla J, Greco N, McNary TJ, Herrscher E, Wilkes D, MacDonald TY, Xue H, Vacic V, Emde AK, Oschwald D, Tan AY, Chen Z, Collins C, Gleave ME, Wang Y, Chakravarty D, Schiffman M, Kim R, Campagne F, Robinson BD, Nanus DM, Tagawa ST, Xiang JZ, Smogorzewska A, Demichelis F, Rickman DS, Sboner A, Elemento O, Rubin MA. Beltran H, et al. Among authors: nanus dm. JAMA Oncol. 2015 Jul;1(4):466-74. doi: 10.1001/jamaoncol.2015.1313. JAMA Oncol. 2015. PMID: 26181256 Free PMC article.
The genomic landscape of metastatic clear cell renal cell carcinoma after systemic therapy.
van der Mijn JC, Eng KW, Chandra P, Fernandez E, Ramazanoglu S, Sigaras A, Oromendia C, Gudas LJ, Tagawa ST, Nanus DM, Faltas BF, Beltran H, Sternberg CN, Elemento O, Sboner A, Mosquera JM, Molina AM. van der Mijn JC, et al. Among authors: nanus dm. Mol Oncol. 2022 Jun;16(12):2384-2395. doi: 10.1002/1878-0261.13204. Epub 2022 Apr 5. Mol Oncol. 2022. PMID: 35231161 Free PMC article.
Integrative Molecular Analysis of Patients With Advanced and Metastatic Cancer.
Sailer V, Eng KW, Zhang T, Bareja R, Pisapia DJ, Sigaras A, Bhinder B, Romanel A, Wilkes D, Sticca E, Cyrta J, Rao R, Sahota S, Pauli C, Beg S, Motanagh S, Kossai M, Fontunge J, Puca L, Rennert H, Zhaoying Xiang J, Greco N, Kim R, MacDonald TY, McNary T, Blattner-Johnson M, Schiffman MH, Faltas BM, Greenfield JP, Rickman D, Andreopoulou E, Holcomb K, Vahdat LT, Scherr DS, van Besien K, Barbieri CE, Robinson BD, Fine HA, Ocean AJ, Molina A, Shah MA, Nanus DM, Pan Q, Demichelis F, Tagawa ST, Song W, Mosquera JM, Sboner A, Rubin MA, Elemento O, Beltran H. Sailer V, et al. Among authors: nanus dm. JCO Precis Oncol. 2019;3:PO.19.00047. doi: 10.1200/PO.19.00047. Epub 2019 Sep 20. JCO Precis Oncol. 2019. PMID: 31592503 Free PMC article.
Common germline-somatic variant interactions in advanced urothelial cancer.
Vosoughi A, Zhang T, Shohdy KS, Vlachostergios PJ, Wilkes DC, Bhinder B, Tagawa ST, Nanus DM, Molina AM, Beltran H, Sternberg CN, Motanagh S, Robinson BD, Xiang J, Fan X, Chung WK, Rubin MA, Elemento O, Sboner A, Mosquera JM, Faltas BM. Vosoughi A, et al. Among authors: nanus dm. Nat Commun. 2020 Dec 3;11(1):6195. doi: 10.1038/s41467-020-19971-8. Nat Commun. 2020. PMID: 33273457 Free PMC article.
Validation of a Circulating Tumor DNA-Based Next-Generation Sequencing Assay in a Cohort of Patients with Solid tumors: A Proposed Solution for Decentralized Plasma Testing.
Al Zoughbi W, Fox J, Beg S, Papp E, Hissong E, Ohara K, Keefer L, Sigouros M, Kane T, Bockelman D, Nichol D, Patchell E, Bareja R, Karandikar A, Alnajar H, Cerqueira G, Guthrie VB, Verner E, Manohar J, Greco N, Wilkes D, Tagawa S, Malbari MS, Holcomb K, Eng KW, Shah M, Altorki NK, Sboner A, Nanus D, Faltas B, Sternberg CN, Simmons J, Houvras Y, Molina AM, Angiuoli S, Elemento O, Mosquera JM. Al Zoughbi W, et al. Oncologist. 2021 Nov;26(11):e1971-e1981. doi: 10.1002/onco.13905. Epub 2021 Aug 4. Oncologist. 2021. PMID: 34286887 Free PMC article.
Challenges in recognizing treatment-related neuroendocrine prostate cancer.
Beltran H, Tagawa ST, Park K, MacDonald T, Milowsky MI, Mosquera JM, Rubin MA, Nanus DM. Beltran H, et al. Among authors: nanus dm. J Clin Oncol. 2012 Dec 20;30(36):e386-9. doi: 10.1200/JCO.2011.41.5166. Epub 2012 Nov 19. J Clin Oncol. 2012. PMID: 23169519 No abstract available.
Clonal evolution of chemotherapy-resistant urothelial carcinoma.
Faltas BM, Prandi D, Tagawa ST, Molina AM, Nanus DM, Sternberg C, Rosenberg J, Mosquera JM, Robinson B, Elemento O, Sboner A, Beltran H, Demichelis F, Rubin MA. Faltas BM, et al. Among authors: nanus dm. Nat Genet. 2016 Dec;48(12):1490-1499. doi: 10.1038/ng.3692. Epub 2016 Oct 17. Nat Genet. 2016. PMID: 27749842 Free PMC article.
Next-Generation Rapid Autopsies Enable Tumor Evolution Tracking and Generation of Preclinical Models.
Pisapia DJ, Salvatore S, Pauli C, Hissong E, Eng K, Prandi D, Sailer VW, Robinson BD, Park K, Cyrta J, Tagawa ST, Kossai M, Fontugne J, Kim R, Sigaras A, Rao R, Pancirer D, Faltas B, Bareja R, Molina AM, Nanus DM, Rajappa P, Souweidane MM, Greenfield J, Emde AK, Robine N, Elemento O, Sboner A, Demichelis F, Beltran H, Rubin MA, Mosquera JM. Pisapia DJ, et al. Among authors: nanus dm. JCO Precis Oncol. 2017;2017:PO.16.00038. doi: 10.1200/PO.16.00038. Epub 2017 Jun 14. JCO Precis Oncol. 2017. PMID: 29333526 Free PMC article.
234 results