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Exploration of the P1 residue in 3CL protease inhibitors leading to the discovery of a 2-tetrahydrofuran P1 replacement.
Bioorg Med Chem. 2024 Feb 15;100:117618. doi: 10.1016/j.bmc.2024.117618. Epub 2024 Jan 29.
Bioorg Med Chem. 2024.
PMID: 38309201
2,4-Diamino-6-methylpyrimidines for the potential treatment of Chagas' disease.
Thomas MG, De Rycker M, Cotillo Torrejon I, Thomas J, Riley J, Spinks D, Read KD, Miles TJ, Gilbert IH, Wyatt PG.
Thomas MG, et al. Among authors: cotillo torrejon i.
Bioorg Med Chem Lett. 2018 Oct 1;28(18):3025-3030. doi: 10.1016/j.bmcl.2018.08.005. Epub 2018 Aug 3.
Bioorg Med Chem Lett. 2018.
PMID: 30104093
Free PMC article.
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