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Exploration of the P1 residue in 3CL protease inhibitors leading to the discovery of a 2-tetrahydrofuran P1 replacement.
Bioorg Med Chem. 2024 Feb 15;100:117618. doi: 10.1016/j.bmc.2024.117618. Epub 2024 Jan 29.
Bioorg Med Chem. 2024.
PMID: 38309201
P2Et Phosphazene: A Mild, Functional Group Tolerant Base for Soluble, Room Temperature Pd-Catalyzed C-N, C-O, and C-C Cross-Coupling Reactions.
Buitrago Santanilla A, Christensen M, Campeau LC, Davies IW, Dreher SD.
Buitrago Santanilla A, et al.
Org Lett. 2015 Jul 2;17(13):3370-3. doi: 10.1021/acs.orglett.5b01648. Epub 2015 Jun 22.
Org Lett. 2015.
PMID: 26099020
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Organic chemistry. Nanomole-scale high-throughput chemistry for the synthesis of complex molecules.
Buitrago Santanilla A, Regalado EL, Pereira T, Shevlin M, Bateman K, Campeau LC, Schneeweis J, Berritt S, Shi ZC, Nantermet P, Liu Y, Helmy R, Welch CJ, Vachal P, Davies IW, Cernak T, Dreher SD.
Buitrago Santanilla A, et al.
Science. 2015 Jan 2;347(6217):49-53. doi: 10.1126/science.1259203. Epub 2014 Nov 20.
Science. 2015.
PMID: 25554781
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