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267 results

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Natural carboxyterminal truncation of human CXCL10 attenuates glycosaminoglycan binding, CXCR3A signaling and lymphocyte chemotaxis, while retaining angiostatic activity.
Dillemans L, Yu K, De Zutter A, Noppen S, Gouwy M, Berghmans N, Verhallen L, De Bondt M, Vanbrabant L, Brusselmans S, Martens E, Schols D, Verschueren P, Rosenkilde MM, Marques PE, Struyf S, Proost P. Dillemans L, et al. Among authors: rosenkilde mm. Cell Commun Signal. 2024 Feb 2;22(1):94. doi: 10.1186/s12964-023-01453-1. Cell Commun Signal. 2024. PMID: 38308278 Free PMC article.
AMD3465, a monomacrocyclic CXCR4 antagonist and potent HIV entry inhibitor.
Hatse S, Princen K, De Clercq E, Rosenkilde MM, Schwartz TW, Hernandez-Abad PE, Skerlj RT, Bridger GJ, Schols D. Hatse S, et al. Among authors: rosenkilde mm. Biochem Pharmacol. 2005 Sep 1;70(5):752-61. doi: 10.1016/j.bcp.2005.05.035. Biochem Pharmacol. 2005. PMID: 16011832 Free article.
Natural nitration of CXCL12 reduces its signaling capacity and chemotactic activity in vitro and abrogates intra-articular lymphocyte recruitment in vivo.
Janssens R, Mortier A, Boff D, Vanheule V, Gouwy M, Franck C, Larsen O, Rosenkilde MM, Van Damme J, Amaral FA, Teixeira MM, Struyf S, Proost P. Janssens R, et al. Among authors: rosenkilde mm. Oncotarget. 2016 Sep 20;7(38):62439-62459. doi: 10.18632/oncotarget.11516. Oncotarget. 2016. PMID: 27566567 Free PMC article.
Truncation of CXCL12 by CD26 reduces its CXC chemokine receptor 4- and atypical chemokine receptor 3-dependent activity on endothelial cells and lymphocytes.
Janssens R, Mortier A, Boff D, Ruytinx P, Gouwy M, Vantilt B, Larsen O, Daugvilaite V, Rosenkilde MM, Parmentier M, Noppen S, Liekens S, Van Damme J, Struyf S, Teixeira MM, Amaral FA, Proost P. Janssens R, et al. Among authors: rosenkilde mm. Biochem Pharmacol. 2017 May 15;132:92-101. doi: 10.1016/j.bcp.2017.03.009. Epub 2017 Mar 18. Biochem Pharmacol. 2017. PMID: 28322746
Peroxynitrite Exposure of CXCL12 Impairs Monocyte, Lymphocyte and Endothelial Cell Chemotaxis, Lymphocyte Extravasation in vivo and Anti-HIV-1 Activity.
Janssens R, Boff D, Ruytinx P, Mortier A, Vanheule V, Larsen O, Daugvilaite V, Rosenkilde MM, Noppen S, Liekens S, Schols D, De Meester I, Opdenakker G, Struyf S, Teixeira MM, Amaral FA, Proost P. Janssens R, et al. Among authors: rosenkilde mm. Front Immunol. 2018 Aug 28;9:1933. doi: 10.3389/fimmu.2018.01933. eCollection 2018. Front Immunol. 2018. PMID: 30233568 Free PMC article.
"Glyco-sulfo barcodes" regulate chemokine receptor function.
Verhallen L, Lackman JJ, Wendt R, Gustavsson M, Yang Z, Narimatsu Y, Sørensen DM, Lafferty KM, Gouwy M, Marques PE, Hjortø GM, Rosenkilde MM, Proost P, Goth CK. Verhallen L, et al. Among authors: rosenkilde mm. Cell Mol Life Sci. 2023 Feb 2;80(2):55. doi: 10.1007/s00018-023-04697-9. Cell Mol Life Sci. 2023. PMID: 36729338 Free PMC article.
267 results