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Chemical modulation of Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) induces wide-scale biological and epigenomic changes.
Padalino G, Celatka CA, Rienhoff HY Jr, Kalin JH, Cole PA, Lassalle D, Forde-Thomas J, Chalmers IW, Brancale A, Grunau C, Hoffmann KF. Padalino G, et al. Among authors: cole pa. Wellcome Open Res. 2023 Mar 30;8:146. doi: 10.12688/wellcomeopenres.18826.1. eCollection 2023. Wellcome Open Res. 2023. PMID: 37520936 Free PMC article.
NEDD4L intramolecular interactions regulate its auto and substrate NaV1.5 ubiquitination.
Wright KM, Nathan S, Jiang H, Xia W, Kim H, Chakouri N, Nwafor JN, Fossier L, Srinivasan L, Chen Z, Boronina T, Post J, Paul S, Cole RN, Ben-Johny M, Cole PA, Gabelli SB. Wright KM, et al. Among authors: cole pa. J Biol Chem. 2024 Mar;300(3):105715. doi: 10.1016/j.jbc.2024.105715. Epub 2024 Feb 2. J Biol Chem. 2024. PMID: 38309503 Free PMC article.
Editorial: Mechanistic biology.
Zhang YJ, Cole PA. Zhang YJ, et al. Among authors: cole pa. Curr Opin Chem Biol. 2023 Jun;74:102283. doi: 10.1016/j.cbpa.2023.102283. Epub 2023 Mar 8. Curr Opin Chem Biol. 2023. PMID: 36898286 No abstract available.
Asymmetric Engagement of Dimeric CRL3 KBTBD4 by the Molecular Glue UM171 Licenses Degradation of HDAC1/2 Complexes.
Yeo MJ, Zhang O, Xie X, Nam E, Payne NC, Gosavi PM, Kwok HS, Iram I, Lee C, Li J, Chen NJ, Jiang H, Wang ZA, Lee K, Mao H, Harry SA, Barakat IA, Takahashi M, Waterbury AL, Barone M, Mattevi A, Bar-Peled L, Cole PA, Mazitschek R, Liau BB, Zheng N. Yeo MJ, et al. Among authors: cole pa. bioRxiv [Preprint]. 2024 May 14:2024.05.14.593897. doi: 10.1101/2024.05.14.593897. bioRxiv. 2024. PMID: 38798619 Free PMC article. Preprint.
KBTBD4 Cancer Hotspot Mutations Drive Neomorphic Degradation of HDAC1/2 Corepressor Complexes.
Xie X, Zhang O, Yeo MJR, Lee C, Harry SA, Paul L, Li Y, Payne NC, Nam E, Kwok HS, Jiang H, Mao H, Hadley JL, Lin H, Batts M, Gosavi PM, D'Angiolella V, Cole PA, Mazitschek R, Northcott PA, Zheng N, Liau BB. Xie X, et al. Among authors: cole pa. bioRxiv [Preprint]. 2024 May 14:2024.05.14.593970. doi: 10.1101/2024.05.14.593970. bioRxiv. 2024. PMID: 38798357 Free PMC article. Preprint.
472 results