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Glutamine-dependent α-ketoglutarate production regulates the balance between T helper 1 cell and regulatory T cell generation.
Klysz D, Tai X, Robert PA, Craveiro M, Cretenet G, Oburoglu L, Mongellaz C, Floess S, Fritz V, Matias MI, Yong C, Surh N, Marie JC, Huehn J, Zimmermann V, Kinet S, Dardalhon V, Taylor N. Klysz D, et al. Among authors: taylor n. Sci Signal. 2015 Sep 29;8(396):ra97. doi: 10.1126/scisignal.aab2610. Sci Signal. 2015. PMID: 26420908
Regulatory T cell differentiation is controlled by αKG-induced alterations in mitochondrial metabolism and lipid homeostasis.
Matias MI, Yong CS, Foroushani A, Goldsmith C, Mongellaz C, Sezgin E, Levental KR, Talebi A, Perrault J, Rivière A, Dehairs J, Delos O, Bertand-Michel J, Portais JC, Wong M, Marie JC, Kelekar A, Kinet S, Zimmermann VS, Levental I, Yvan-Charvet L, Swinnen JV, Muljo SA, Hernandez-Vargas H, Tardito S, Taylor N, Dardalhon V. Matias MI, et al. Among authors: taylor n. Cell Rep. 2021 Nov 2;37(5):109911. doi: 10.1016/j.celrep.2021.109911. Cell Rep. 2021. PMID: 34731632 Free PMC article.
Glutamine promotes the generation of B10+ cells via the mTOR/GSK3 pathway.
Mielle J, Morel J, Elhmioui J, Combe B, Macia L, Dardalhon V, Taylor N, Audo R, Daien C. Mielle J, et al. Among authors: taylor n. Eur J Immunol. 2022 Mar;52(3):418-430. doi: 10.1002/eji.202149387. Epub 2022 Feb 1. Eur J Immunol. 2022. PMID: 34961940 Free article.
CAR T-cell therapy of solid tumors.
Yong CSM, Dardalhon V, Devaud C, Taylor N, Darcy PK, Kershaw MH. Yong CSM, et al. Among authors: taylor n. Immunol Cell Biol. 2017 Apr;95(4):356-363. doi: 10.1038/icb.2016.128. Epub 2016 Dec 22. Immunol Cell Biol. 2017. PMID: 28003642 Review.
Metabolic orchestration of T lineage differentiation and function.
Yong CS, Abba Moussa D, Cretenet G, Kinet S, Dardalhon V, Taylor N. Yong CS, et al. Among authors: taylor n. FEBS Lett. 2017 Oct;591(19):3104-3118. doi: 10.1002/1873-3468.12849. Epub 2017 Oct 6. FEBS Lett. 2017. PMID: 28901530 Free article. Review.
2,628 results