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Role of Lu/BCAM glycoproteins in red cell diseases.
El Nemer W, Colin Y, Le Van Kim C. El Nemer W, et al. Transfus Clin Biol. 2010 Sep;17(3):143-7. doi: 10.1016/j.tracli.2010.06.002. Epub 2010 Jul 23. Transfus Clin Biol. 2010. PMID: 20655789
Long-term outcomes of lentiviral gene therapy for the β-hemoglobinopathies: the HGB-205 trial.
Magrin E, Semeraro M, Hebert N, Joseph L, Magnani A, Chalumeau A, Gabrion A, Roudaut C, Marouene J, Lefrere F, Diana JS, Denis A, Neven B, Funck-Brentano I, Negre O, Renolleau S, Brousse V, Kiger L, Touzot F, Poirot C, Bourget P, El Nemer W, Blanche S, Tréluyer JM, Asmal M, Walls C, Beuzard Y, Schmidt M, Hacein-Bey-Abina S, Asnafi V, Guichard I, Poirée M, Monpoux F, Touraine P, Brouzes C, de Montalembert M, Payen E, Six E, Ribeil JA, Miccio A, Bartolucci P, Leboulch P, Cavazzana M. Magrin E, et al. Among authors: el nemer w. Nat Med. 2022 Jan;28(1):81-88. doi: 10.1038/s41591-021-01650-w. Epub 2022 Jan 24. Nat Med. 2022. PMID: 35075288 Clinical Trial.
Endothelial Cells Harbouring the JAK2V617F Mutation Display Pro-Adherent and Pro-Thrombotic Features.
Guadall A, Lesteven E, Letort G, Awan Toor S, Delord M, Pognant D, Brusson M, Verger E, Maslah N, Giraudier S, Larghero J, Vanneaux V, Chomienne C, El Nemer W, Cassinat B, Kiladjian JJ. Guadall A, et al. Among authors: el nemer w. Thromb Haemost. 2018 Sep;118(9):1586-1599. doi: 10.1055/s-0038-1667015. Epub 2018 Aug 13. Thromb Haemost. 2018. PMID: 30103245
A microfluidic approach to study the effect of mechanical stress on erythrocytes in sickle cell disease.
Lizarralde Iragorri MA, El Hoss S, Brousse V, Lefevre SD, Dussiot M, Xu T, Ferreira AR, Lamarre Y, Silva Pinto AC, Kashima S, Lapouméroulie C, Covas DT, Le Van Kim C, Colin Y, Elion J, Français O, Le Pioufle B, El Nemer W. Lizarralde Iragorri MA, et al. Among authors: el hoss s, el nemer w. Lab Chip. 2018 Sep 26;18(19):2975-2984. doi: 10.1039/c8lc00637g. Lab Chip. 2018. PMID: 30168832
Red cell and endothelial Lu/BCAM beyond sickle cell disease.
Colin Y, Rahuel C, Wautier MP, El Nemer W, Filipe A, Cartron JP, Le Van Kim C, Wautier JL. Colin Y, et al. Among authors: el nemer w. Transfus Clin Biol. 2008 Dec;15(6):402-5. doi: 10.1016/j.tracli.2008.07.011. Epub 2008 Oct 22. Transfus Clin Biol. 2008. PMID: 18948049
Oxidative stress activates red cell adhesion to laminin in sickle cell disease.
Lizarralde-Iragorri MA, Lefevre SD, Cochet S, El Hoss S, Brousse V, Filipe A, Dussiot M, Azouzi S, Le Van Kim C, Rodrigues-Lima F, Français O, Le Pioufle B, Klei T, van Bruggen R, El Nemer W. Lizarralde-Iragorri MA, et al. Among authors: el hoss s, el nemer w. Haematologica. 2021 Sep 1;106(9):2478-2488. doi: 10.3324/haematol.2020.261586. Haematologica. 2021. PMID: 32855277 Free PMC article.
Hydroxycarbamide decreases sickle reticulocyte adhesion to resting endothelium by inhibiting endothelial lutheran/basal cell adhesion molecule (Lu/BCAM) through phosphodiesterase 4A activation.
Chaar V, Laurance S, Lapoumeroulie C, Cochet S, De Grandis M, Colin Y, Elion J, Le Van Kim C, El Nemer W. Chaar V, et al. Among authors: el nemer w. J Biol Chem. 2014 Apr 18;289(16):11512-11521. doi: 10.1074/jbc.M113.506121. Epub 2014 Mar 10. J Biol Chem. 2014. PMID: 24616094 Free PMC article.
84 results