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The molecular mechanism of on-demand sterol biosynthesis at organelle contact sites.
Zung N, Aravindan N, Boshnakovska A, Valenti R, Preminger N, Jonas F, Yaakov G, Willoughby MM, Homberg B, Keller J, Kupervaser M, Dezorella N, Dadosh T, Wolf SG, Itkin M, Malitsky S, Brandis A, Barkai N, Fernández-Busnadiego R, Reddi AR, Rehling P, Rapaport D, Schuldiner M. Zung N, et al. Among authors: fernandez busnadiego r. bioRxiv [Preprint]. 2024 May 12:2024.05.09.593285. doi: 10.1101/2024.05.09.593285. bioRxiv. 2024. PMID: 38766039 Free PMC article. Preprint.
In situ studies of membrane biology by cryo-electron tomography.
Keller J, Fernández-Busnadiego R. Keller J, et al. Among authors: fernandez busnadiego r. Curr Opin Cell Biol. 2024 Apr 26;88:102363. doi: 10.1016/j.ceb.2024.102363. Online ahead of print. Curr Opin Cell Biol. 2024. PMID: 38677049 Free article. Review.
A metabolically controlled contact site between vacuoles and lipid droplets in yeast.
Diep DTV, Collado J, Hugenroth M, Fausten RM, Percifull L, Wälte M, Schuberth C, Schmidt O, Fernández-Busnadiego R, Bohnert M. Diep DTV, et al. Among authors: fernandez busnadiego r. Dev Cell. 2024 Mar 25;59(6):740-758.e10. doi: 10.1016/j.devcel.2024.01.016. Epub 2024 Feb 16. Dev Cell. 2024. PMID: 38367622 Free article.
Mammalian oocytes store proteins for the early embryo on cytoplasmic lattices.
Jentoft IMA, Bäuerlein FJB, Welp LM, Cooper BH, Petrovic A, So C, Penir SM, Politi AZ, Horokhovskyi Y, Takala I, Eckel H, Moltrecht R, Lénárt P, Cavazza T, Liepe J, Brose N, Urlaub H, Fernández-Busnadiego R, Schuh M. Jentoft IMA, et al. Among authors: fernandez busnadiego r. Cell. 2023 Nov 22;186(24):5308-5327.e25. doi: 10.1016/j.cell.2023.10.003. Epub 2023 Nov 2. Cell. 2023. PMID: 37922900 Free article.
The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system.
Saha I, Yuste-Checa P, Da Silva Padilha M, Guo Q, Körner R, Holthusen H, Trinkaus VA, Dudanova I, Fernández-Busnadiego R, Baumeister W, Sanders DW, Gautam S, Diamond MI, Hartl FU, Hipp MS. Saha I, et al. Among authors: fernandez busnadiego r. Nat Commun. 2023 Feb 2;14(1):560. doi: 10.1038/s41467-023-36058-2. Nat Commun. 2023. PMID: 36732333 Free PMC article.
Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons.
Riemenschneider H, Guo Q, Bader J, Frottin F, Farny D, Kleinberger G, Haass C, Mann M, Hartl FU, Baumeister W, Hipp MS, Meissner F, Fernández-Busnadiego R, Edbauer D. Riemenschneider H, et al. Among authors: fernandez busnadiego r. EMBO Rep. 2022 Jun 7;23(6):e53890. doi: 10.15252/embr.202153890. Epub 2022 Apr 19. EMBO Rep. 2022. PMID: 35438230 Free PMC article.
Amyloid-like aggregating proteins cause lysosomal defects in neurons via gain-of-function toxicity.
Riera-Tur I, Schäfer T, Hornburg D, Mishra A, da Silva Padilha M, Fernández-Mosquera L, Feigenbutz D, Auer P, Mann M, Baumeister W, Klein R, Meissner F, Raimundo N, Fernández-Busnadiego R, Dudanova I. Riera-Tur I, et al. Among authors: fernandez busnadiego r. Life Sci Alliance. 2021 Dec 21;5(3):e202101185. doi: 10.26508/lsa.202101185. Print 2022 Mar. Life Sci Alliance. 2021. PMID: 34933920 Free PMC article.
Cnm1 mediates nucleus-mitochondria contact site formation in response to phospholipid levels.
Eisenberg-Bord M, Zung N, Collado J, Drwesh L, Fenech EJ, Fadel A, Dezorella N, Bykov YS, Rapaport D, Fernandez-Busnadiego R, Schuldiner M. Eisenberg-Bord M, et al. Among authors: fernandez busnadiego r. J Cell Biol. 2021 Nov 1;220(11):e202104100. doi: 10.1083/jcb.202104100. Epub 2021 Oct 25. J Cell Biol. 2021. PMID: 34694322 Free PMC article.
38 results