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Design of protein-binding peptides with controlled binding affinity: the case of SARS-CoV-2 receptor binding domain and angiotensin-converting enzyme 2 derived peptides.
Parisi G, Piacentini R, Incocciati A, Bonamore A, Macone A, Rupert J, Zacco E, Miotto M, Milanetti E, Tartaglia GG, Ruocco G, Boffi A, Di Rienzo L. Parisi G, et al. Front Mol Biosci. 2024 Jan 5;10:1332359. doi: 10.3389/fmolb.2023.1332359. eCollection 2023. Front Mol Biosci. 2024. PMID: 38250735 Free PMC article.
Substrate-induced conformational change in cytochrome P450 OleP.
Parisi G, Montemiglio LC, Giuffrè A, Macone A, Scaglione A, Cerutti G, Exertier C, Savino C, Vallone B. Parisi G, et al. FASEB J. 2019 Feb;33(2):1787-1800. doi: 10.1096/fj.201800450RR. Epub 2018 Sep 12. FASEB J. 2019. PMID: 30207799
Data reported herein provide structural snapshots of key precatalytic steps in the OleP reaction and explain how structural rearrangements induced by substrate binding regulate activity.-Parisi, G., Montemiglio, L. C., Giuffre, A., Macone, A., Scaglione, A., Cerutti …
Data reported herein provide structural snapshots of key precatalytic steps in the OleP reaction and explain how structural rearrangements i …
Cytosolic localization and in vitro assembly of human de novo thymidylate synthesis complex.
Spizzichino S, Boi D, Boumis G, Lucchi R, Liberati FR, Capelli D, Montanari R, Pochetti G, Piacentini R, Parisi G, Paone A, Rinaldo S, Contestabile R, Tramonti A, Paiardini A, Giardina G, Cutruzzolà F. Spizzichino S, et al. Among authors: parisi g. FEBS J. 2022 Mar;289(6):1625-1649. doi: 10.1111/febs.16248. Epub 2021 Nov 12. FEBS J. 2022. PMID: 34694685 Free PMC article.
Effect of Salts on the Conformational Dynamics of the Cytochrome P450 OleP.
De Sciscio ML, Nardi AN, Parisi G, Bulfaro G, Costanzo A, Gugole E, Exertier C, Freda I, Savino C, Vallone B, Montemiglio LC, D'Abramo M. De Sciscio ML, et al. Among authors: parisi g. Molecules. 2023 Jan 13;28(2):832. doi: 10.3390/molecules28020832. Molecules. 2023. PMID: 36677890 Free PMC article.
Neuroglobin, clues to function and mechanism.
Exertier C, Montemiglio LC, Freda I, Gugole E, Parisi G, Savino C, Vallone B. Exertier C, et al. Among authors: parisi g. Mol Aspects Med. 2022 Apr;84:101055. doi: 10.1016/j.mam.2021.101055. Epub 2021 Dec 6. Mol Aspects Med. 2022. PMID: 34876274 Review.
Point Mutations at a Key Site Alter the Cytochrome P450 OleP Structural Dynamics.
Montemiglio LC, Gugole E, Freda I, Exertier C, D'Auria L, Chen CG, Nardi AN, Cerutti G, Parisi G, D'Abramo M, Savino C, Vallone B. Montemiglio LC, et al. Among authors: parisi g. Biomolecules. 2021 Dec 31;12(1):55. doi: 10.3390/biom12010055. Biomolecules. 2021. PMID: 35053203 Free PMC article.
719 results