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Development of small-molecule Tau-SH3 interaction inhibitors that prevent amyloid-β toxicity and network hyperexcitability.
Roth JR, Rush T, Thompson SJ, Aldaher AR, Dunn TB, Mesina JS, Cochran JN, Boyle NR, Dean HB, Yang Z, Pathak V, Ruiz P, Wu M, Day JJ, Bostwick JR, Suto MJ, Augelli-Szafran CE, Roberson ED. Roth JR, et al. Among authors: boyle nr. Neurotherapeutics. 2024 Jan;21(1):e00291. doi: 10.1016/j.neurot.2023.10.001. Epub 2023 Dec 19. Neurotherapeutics. 2024. PMID: 38241154 Free PMC article.
Patients with sporadic FTLD exhibit similar increases in lysosomal proteins and storage material as patients with FTD due to GRN mutations.
Davis SE, Cook AK, Hall JA, Voskobiynyk Y, Carullo NV, Boyle NR, Hakim AR, Anderson KM, Hobdy KP, Pugh DA, Murchison CF, McMeekin LJ, Simmons M, Margolies KA, Cowell RM, Nana AL, Spina S, Grinberg LT, Miller BL, Seeley WW, Arrant AE. Davis SE, et al. Among authors: boyle nr. Acta Neuropathol Commun. 2023 Apr 28;11(1):70. doi: 10.1186/s40478-023-01571-4. Acta Neuropathol Commun. 2023. PMID: 37118844 Free PMC article.
Inactivation of HCoV-NL63 and SARS-CoV-2 in aqueous solution by 254 nm UV-C.
Li LX, Nissly RH, Swaminathan A, Bird IM, Boyle NR, Nair MS, Greenawalt DI, Gontu A, Cavener VS, Sornberger T, Freihaut JD, Kuchipudi SV, Bahnfleth WP. Li LX, et al. Among authors: boyle nr. J Photochem Photobiol B. 2023 Aug;245:112755. doi: 10.1016/j.jphotobiol.2023.112755. Epub 2023 Jul 5. J Photochem Photobiol B. 2023. PMID: 37423001
32 results