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Plasma steroid concentrations reflect acute disease severity and normalise during recovery in people hospitalised with COVID-19.
Devine K, Russell CD, Blanco GR, Walker BR, Homer NZM, Denham SG, Simpson JP, Leavy OC, Elneima O, McAuley HJC, Shikotra A, Singapuri A, Sereno M, Saunders RM, Harris VC, Houchen-Wolloff L, Greening NJ, Lone NI, Thorpe M, Greenhalf W, Chalmers JD, Ho LP, Horsley A, Marks M, Raman B, Moore SC, Dunning J, Semple MG, Andrew R, Wain LV, Evans RA, Brightling CE, Kenneth Baillie J, Reynolds RM; ISARIC4C Investigators and PHOSP-COVID Study Collaborative Group. Devine K, et al. Among authors: simpson jp. Clin Endocrinol (Oxf). 2024 Apr;100(4):317-327. doi: 10.1111/cen.15012. Epub 2024 Jan 17. Clin Endocrinol (Oxf). 2024. PMID: 38229583
Derivatization with 2-hydrazino-1-methylpyridine enhances sensitivity of analysis of 5α-dihydrotestosterone in human plasma by liquid chromatography tandem mass spectrometry.
Faqehi AM, Denham SG, Naredo G, Cobice DF, Khan S, Simpson JP, Sabil G, Upreti R, Gibb F, Homer NZ, Andrew R. Faqehi AM, et al. Among authors: simpson jp. J Chromatogr A. 2021 Mar 15;1640:461933. doi: 10.1016/j.chroma.2021.461933. Epub 2021 Jan 23. J Chromatogr A. 2021. PMID: 33588275 Free PMC article.
The serotonin transporter sustains human brown adipose tissue thermogenesis.
Suchacki KJ, Ramage LE, Kwok TC, Kelman A, McNeill BT, Rodney S, Keegan M, Gray C, MacNaught G, Patel D, Fletcher AM, Simpson JP, Carter RN, Semple RK, Homer NZM, Morton NM, van Beek EJR, Wakelin SJ, Stimson RH. Suchacki KJ, et al. Among authors: simpson jp. Nat Metab. 2023 Aug;5(8):1319-1336. doi: 10.1038/s42255-023-00839-2. Epub 2023 Aug 3. Nat Metab. 2023. PMID: 37537371 Free PMC article.
Dimethyl fumarate reduces hepatocyte senescence following paracetamol exposure.
Meseguer-Ripolles J, Lucendo-Villarin B, Tucker C, Ferreira-Gonzalez S, Homer N, Wang Y, Starkey Lewis PJ, M Toledo E, Mellado-Gomez E, Simpson J, Flint O, Jaiswal H, Beer NL, Karlsen AE, Forbes SJ, Dear JW, Hughes J, Hay DC. Meseguer-Ripolles J, et al. iScience. 2021 May 19;24(6):102552. doi: 10.1016/j.isci.2021.102552. eCollection 2021 Jun 25. iScience. 2021. PMID: 34151225 Free PMC article.
Ionisation bias undermines the use of matrix-assisted laser desorption/ionisation for estimating peptide deamidation: Synthetic peptide studies demonstrate electrospray ionisation gives more reliable response ratios.
Simpson JP, Fascione M, Bergström E, Wilson J, Collins MJ, Penkman KEH, Thomas-Oates J. Simpson JP, et al. Rapid Commun Mass Spectrom. 2019 Jun 30;33(12):1049-1057. doi: 10.1002/rcm.8441. Rapid Commun Mass Spectrom. 2019. PMID: 30908787 Free PMC article.
56 results