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SUMOylation modulates eIF5A activities in both yeast and pancreatic ductal adenocarcinoma cells.
Seoane R, Lama-Díaz T, Romero AM, El Motiam A, Martínez-Férriz A, Vidal S, Bouzaher YH, Blanquer M, Tolosa RM, Castillo Mewa J, Rodríguez MS, García-Sastre A, Xirodimas D, Sutherland JD, Barrio R, Alepuz P, Blanco MG, Farràs R, Rivas C. Seoane R, et al. Among authors: farras r. Cell Mol Biol Lett. 2024 Jan 16;29(1):15. doi: 10.1186/s11658-024-00533-5. Cell Mol Biol Lett. 2024. PMID: 38229033 Free PMC article.
Down-regulation of c-Fos/c-Jun AP-1 dimer activity by sumoylation.
Bossis G, Malnou CE, Farras R, Andermarcher E, Hipskind R, Rodriguez M, Schmidt D, Muller S, Jariel-Encontre I, Piechaczyk M. Bossis G, et al. Among authors: farras r. Mol Cell Biol. 2005 Aug;25(16):6964-79. doi: 10.1128/MCB.25.16.6964-6979.2005. Mol Cell Biol. 2005. PMID: 16055710 Free PMC article.
eIF5A is activated by virus infection or dsRNA and facilitates virus replication through modulation of interferon production.
Seoane R, Llamas-González YY, Vidal S, El Motiam A, Bouzaher YH, Fonseca D, Farrás R, García-Sastre A, González-Santamaría J, Rivas C. Seoane R, et al. Among authors: farras r. Front Cell Infect Microbiol. 2022 Jul 27;12:960138. doi: 10.3389/fcimb.2022.960138. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 35967877 Free PMC article.
Ubiquitin-mediated mechanisms of translational control.
Martínez-Férriz A, Ferrando A, Fathinajafabadi A, Farràs R. Martínez-Férriz A, et al. Among authors: farras r. Semin Cell Dev Biol. 2022 Dec;132:146-154. doi: 10.1016/j.semcdb.2021.12.009. Epub 2021 Dec 21. Semin Cell Dev Biol. 2022. PMID: 34952788 Review.
New roles for AP-1/JUNB in cell cycle control and tumorigenic cell invasion via regulation of cyclin E1 and TGF-β2.
Pérez-Benavente B, Fathinajafabadi A, de la Fuente L, Gandía C, Martínez-Férriz A, Pardo-Sánchez JM, Milián L, Conesa A, Romero OA, Carretero J, Matthiesen R, Jariel-Encontre I, Piechaczyk M, Farràs R. Pérez-Benavente B, et al. Among authors: farras r. Genome Biol. 2022 Dec 9;23(1):252. doi: 10.1186/s13059-022-02800-0. Genome Biol. 2022. PMID: 36494864 Free PMC article.
Tetramerization-defects of p53 result in aberrant ubiquitylation and transcriptional activity.
Lang V, Pallara C, Zabala A, Lobato-Gil S, Lopitz-Otsoa F, Farrás R, Hjerpe R, Torres-Ramos M, Zabaleta L, Blattner C, Hay RT, Barrio R, Carracedo A, Fernandez-Recio J, Rodríguez MS, Aillet F. Lang V, et al. Among authors: farras r. Mol Oncol. 2014 Jul;8(5):1026-42. doi: 10.1016/j.molonc.2014.04.002. Epub 2014 Apr 13. Mol Oncol. 2014. PMID: 24816189 Free PMC article.
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