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The Piezo channel is a mechano-sensitive complex component in the mammalian inner ear hair cell.
Lee JH, Perez-Flores MC, Park S, Kim HJ, Chen Y, Kang M, Kersigo J, Choi J, Thai PN, Woltz RL, Perez-Flores DC, Perkins G, Sihn CR, Trinh P, Zhang XD, Sirish P, Dong Y, Feng WW, Pessah IN, Dixon RE, Sokolowski B, Fritzsch B, Chiamvimonvat N, Yamoah EN. Lee JH, et al. Among authors: sirish p. Nat Commun. 2024 Jan 16;15(1):526. doi: 10.1038/s41467-023-44230-x. Nat Commun. 2024. PMID: 38228630 Free PMC article.
The Piezo channel is central to the mechano-sensitive channel complex in the mammalian inner ear.
Lee JH, Perez-Flores MC, Park S, Kim HJ, Chen Y, Kang M, Kersigo J, Choi J, Thai PN, Woltz R, Perez-Flores DC, Perkins G, Sihn CR, Trinh P, Zhang XD, Sirish P, Dong Y, Feng WW, Pessah IN, Dixon RE, Sokolowski B, Fritzsch B, Chiamvimonvat N, Yamoah EN. Lee JH, et al. Among authors: sirish p. Res Sq [Preprint]. 2023 Jul 12:rs.3.rs-2287052. doi: 10.21203/rs.3.rs-2287052/v1. Res Sq. 2023. PMID: 37502846 Free PMC article. Updated. Preprint.
Action Potential Shortening and Impairment of Cardiac Function by Ablation of Slc26a6.
Sirish P, Ledford HA, Timofeyev V, Thai PN, Ren L, Kim HJ, Park S, Lee JH, Dai G, Moshref M, Sihn CR, Chen WC, Timofeyeva MV, Jian Z, Shimkunas R, Izu LT, Chiamvimonvat N, Chen-Izu Y, Yamoah EN, Zhang XD. Sirish P, et al. Circ Arrhythm Electrophysiol. 2017 Oct;10(10):e005267. doi: 10.1161/CIRCEP.117.005267. Circ Arrhythm Electrophysiol. 2017. PMID: 29025768 Free PMC article.
AKAP5 complex facilitates purinergic modulation of vascular L-type Ca2+ channel CaV1.2.
Prada MP, Syed AU, Reddy GR, Martín-Aragón Baudel M, Flores-Tamez VA, Sasse KC, Ward SM, Sirish P, Chiamvimonvat N, Bartels P, Dickson EJ, Hell JW, Scott JD, Santana LF, Xiang YK, Navedo MF, Nieves-Cintrón M. Prada MP, et al. Among authors: sirish p. Nat Commun. 2020 Oct 20;11(1):5303. doi: 10.1038/s41467-020-18947-y. Nat Commun. 2020. PMID: 33082339 Free PMC article.
Disruption of protein quality control of the human ether-à-go-go related gene K+ channel results in profound long QT syndrome.
Ledford HA, Ren L, Thai PN, Park S, Timofeyev V, Sirish P, Xu W, Emigh AM, Priest JR, Perez MV, Ashley EA, Yarov-Yarovoy V, Yamoah EN, Zhang XD, Chiamvimonvat N. Ledford HA, et al. Among authors: sirish p. Heart Rhythm. 2022 Feb;19(2):281-292. doi: 10.1016/j.hrthm.2021.10.005. Epub 2021 Oct 9. Heart Rhythm. 2022. PMID: 34634443 Free PMC article.
Disruption of mitochondria-sarcoplasmic reticulum microdomain connectomics contributes to sinus node dysfunction in heart failure.
Ren L, Gopireddy RR, Perkins G, Zhang H, Timofeyev V, Lyu Y, Diloretto DA, Trinh P, Sirish P, Overton JL, Xu W, Grainger N, Xiang YK, Dedkova EN, Zhang XD, Yamoah EN, Navedo MF, Thai PN, Chiamvimonvat N. Ren L, et al. Among authors: sirish p. Proc Natl Acad Sci U S A. 2022 Sep 6;119(36):e2206708119. doi: 10.1073/pnas.2206708119. Epub 2022 Aug 31. Proc Natl Acad Sci U S A. 2022. PMID: 36044551 Free PMC article.
Adenylyl cyclase subtype-specific compartmentalization: differential regulation of L-type Ca2+ current in ventricular myocytes.
Timofeyev V, Myers RE, Kim HJ, Woltz RL, Sirish P, Heiserman JP, Li N, Singapuri A, Tang T, Yarov-Yarovoy V, Yamoah EN, Hammond HK, Chiamvimonvat N. Timofeyev V, et al. Among authors: sirish p. Circ Res. 2013 Jun 7;112(12):1567-76. doi: 10.1161/CIRCRESAHA.112.300370. Epub 2013 Apr 22. Circ Res. 2013. PMID: 23609114 Free PMC article.
30 results