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Sex-specific hypnotic effects of the neuroactive steroid (3β,5β,17β)-3-hydroxyandrostane-17-carbonitrile are mediated by peripheral metabolism into an active hypnotic steroid.
Manzella FM, Cabrera OH, Wilkey D, Fine-Raquet B, Klawitter J, Krishnan K, Covey DF, Jevtovic-Todorovic V, Todorovic SM. Manzella FM, et al. Among authors: covey df. Br J Anaesth. 2023 Feb;130(2):154-164. doi: 10.1016/j.bja.2022.09.025. Epub 2022 Nov 22. Br J Anaesth. 2023. PMID: 36428160 Free PMC article.
Neurosteroid enantiomers as potentially novel neurotherapeutics.
Covey DF, Evers AS, Izumi Y, Maguire JL, Mennerick SJ, Zorumski CF. Covey DF, et al. Neurosci Biobehav Rev. 2023 Jun;149:105191. doi: 10.1016/j.neubiorev.2023.105191. Epub 2023 Apr 20. Neurosci Biobehav Rev. 2023. PMID: 37085023 Free PMC article. Review.
The Mechanism of Enantioselective Neurosteroid Actions on GABAA Receptors.
Tateiwa H, Chintala SM, Chen Z, Wang L, Amtashar F, Bracamontes J, Germann AL, Pierce SR, Covey DF, Akk G, Evers AS. Tateiwa H, et al. Among authors: covey df. Biomolecules. 2023 Feb 9;13(2):341. doi: 10.3390/biom13020341. Biomolecules. 2023. PMID: 36830708 Free PMC article.
Neonatal exposure to a neuroactive steroid alters low-frequency oscillations in the subiculum.
Fine-Raquet B, Manzella FM, Joksimovic SM, Dietz RM, Orfila JE, Sampath D, Tesic V, Atluri N, Covey DF, Raol YH, Jevtovic-Todorovic V, Herson PS, Todorovic SM. Fine-Raquet B, et al. Among authors: covey df. Exp Biol Med (Maywood). 2023 Apr;248(7):578-587. doi: 10.1177/15353702231177009. Epub 2023 Jun 13. Exp Biol Med (Maywood). 2023. PMID: 37309730 Free PMC article.
Natamycin interferes with ergosterol-dependent lipid phases in model membranes.
Akkerman V, Scheidt HA, Reinholdt P, Bashawat M, Szomek M, Lehmann M, Wessig P, Covey DF, Kongsted J, Müller P, Wüstner D. Akkerman V, et al. Among authors: covey df. BBA Adv. 2023 Aug 25;4:100102. doi: 10.1016/j.bbadva.2023.100102. eCollection 2023. BBA Adv. 2023. PMID: 37691996 Free PMC article.
Ergosterol promotes aggregation of natamycin in the yeast plasma membrane.
Szomek M, Akkerman V, Lauritsen L, Walther HL, Juhl AD, Thaysen K, Egebjerg JM, Covey DF, Lehmann M, Wessig P, Foster AJ, Poolman B, Werner S, Schneider G, Müller P, Wüstner D. Szomek M, et al. Among authors: covey df. Biochim Biophys Acta Biomembr. 2024 May 27;1866(7):184350. doi: 10.1016/j.bbamem.2024.184350. Online ahead of print. Biochim Biophys Acta Biomembr. 2024. PMID: 38806103
GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway.
Hoppe N, Harrison S, Hwang SH, Chen Z, Karelina M, Deshpande I, Suomivuori CM, Palicharla VR, Berry SP, Tschaikner P, Regele D, Covey DF, Stefan E, Marks DS, Reiter J, Dror RO, Evers AS, Mukhopadhyay S, Manglik A. Hoppe N, et al. Among authors: covey df. bioRxiv [Preprint]. 2023 May 24:2023.05.23.540554. doi: 10.1101/2023.05.23.540554. bioRxiv. 2023. PMID: 37292845 Free PMC article. Updated. Preprint.
335 results