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Conversion of monoclonal IgG to dimeric and secretory IgA restores neutralizing ability and prevents infection of Omicron lineages.
Marcotte H, Cao Y, Zuo F, Simonelli L, Sammartino JC, Pedotti M, Sun R, Cassaniti I, Hagbom M, Piralla A, Yang J, Du L, Percivalle E, Bertoglio F, Schubert M, Abolhassani H, Sherina N, Guerra C, Borte S, Rezaei N, Kumagai-Braesch M, Xue Y, Su C, Yan Q, He P, Grönwall C, Klareskog L, Calzolai L, Cavalli A, Wang Q, Robbiani DF, Hust M, Shi Z, Feng L, Svensson L, Chen L, Bao L, Baldanti F, Xiao J, Qin C, Hammarström L, Yang X, Varani L, Xie XS, Pan-Hammarström Q. Marcotte H, et al. Among authors: yan q. Proc Natl Acad Sci U S A. 2024 Jan 16;121(3):e2315354120. doi: 10.1073/pnas.2315354120. Epub 2024 Jan 9. Proc Natl Acad Sci U S A. 2024. PMID: 38194459 Free PMC article.
Convalescent patient-derived monoclonal antibodies targeting different epitopes of E protein confer protection against Zika virus in a neonatal mouse model.
Niu X, Zhao L, Qu L, Yao Z, Zhang F, Yan Q, Zhang S, Liang R, Chen P, Luo J, Xu W, Lv H, Liu X, Lei H, Yi C, Li P, Wang Q, Wang Y, Yu L, Zhang X, Bryan LA, Davidson E, Doranz JB, Feng L, Pan W, Zhang F, Chen L. Niu X, et al. Among authors: yan q. Emerg Microbes Infect. 2019;8(1):749-759. doi: 10.1080/22221751.2019.1614885. Emerg Microbes Infect. 2019. PMID: 31130109 Free PMC article.
Longitudinal analysis of the antibody repertoire of a Zika virus-infected patient revealed dynamic changes in antibody response.
Niu X, Yan Q, Yao Z, Zhang F, Qu L, Wang C, Wang C, Lei H, Chen C, Liang R, Luo J, Wang Q, Zhao L, Zhang Y, Luo K, Wang L, Wu H, Liu T, Li P, Zheng Z, Tan YJ, Feng L, Zhang Z, Han J, Zhang F, Chen L. Niu X, et al. Among authors: yan q. Emerg Microbes Infect. 2020 Jan 6;9(1):111-123. doi: 10.1080/22221751.2019.1701953. eCollection 2020. Emerg Microbes Infect. 2020. PMID: 31906823 Free PMC article.
Germline IGHV3-53-encoded RBD-targeting neutralizing antibodies are commonly present in the antibody repertoires of COVID-19 patients.
Yan Q, He P, Huang X, Luo K, Zhang Y, Yi H, Wang Q, Li F, Hou R, Fan X, Li P, Liu X, Liang H, Deng Y, Chen Z, Chen Y, Mo X, Feng L, Xiong X, Li S, Han J, Qu L, Niu X, Chen L. Yan Q, et al. Emerg Microbes Infect. 2021 Dec;10(1):1097-1111. doi: 10.1080/22221751.2021.1925594. Emerg Microbes Infect. 2021. PMID: 33944697 Free PMC article.
A Class of Shark-Derived Single-Domain Antibodies can Broadly Neutralize SARS-Related Coronaviruses and the Structural Basis of Neutralization and Omicron Escape.
Feng B, Chen Z, Sun J, Xu T, Wang Q, Yi H, Niu X, Zhu J, Fan M, Hou R, Shao Y, Huang S, Li C, Hu P, Zheng P, He P, Luo J, Yan Q, Xiong X, Liu J, Zhao J, Chen L. Feng B, et al. Among authors: yan q. Small Methods. 2022 Jul;6(7):e2200387. doi: 10.1002/smtd.202200387. Epub 2022 May 18. Small Methods. 2022. PMID: 35583124 Free PMC article.
SARS-CoV-2 Delta and Omicron variants evade population antibody response by mutations in a single spike epitope.
He P, Liu B, Gao X, Yan Q, Pei R, Sun J, Chen Q, Hou R, Li Z, Zhang Y, Zhao J, Sun H, Feng B, Wang Q, Yi H, Hu P, Li P, Zhang Y, Chen Z, Niu X, Zhong X, Jin L, Liu X, Qu K, Ciazynska KA, Carter AP, Briggs JAG, Chen J, Liu J, Chen X, He J, Chen L, Xiong X. He P, et al. Among authors: yan q. Nat Microbiol. 2022 Oct;7(10):1635-1649. doi: 10.1038/s41564-022-01235-4. Epub 2022 Sep 23. Nat Microbiol. 2022. PMID: 36151403 Free PMC article.
5,117 results