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A cis-regulatory element regulates ERAP2 expression through autoimmune disease risk SNPs.
Venema WJ, Hiddingh S, van Loosdregt J, Bowes J, Balliu B, de Boer JH, Ossewaarde-van Norel J, Thompson SD, Langefeld CD, de Ligt A, van der Veken LT, Krijger PHL, de Laat W, Kuiper JJW. Venema WJ, et al. Among authors: hiddingh s. Cell Genom. 2024 Jan 10;4(1):100460. doi: 10.1016/j.xgen.2023.100460. Epub 2023 Dec 5. Cell Genom. 2024. PMID: 38190099 Free PMC article.
Association of Risk Variants in the CFH Gene With Elevated Levels of Coagulation and Complement Factors in Idiopathic Multifocal Choroiditis.
de Groot EL, Ossewaarde-van Norel J, de Boer JH, Hiddingh S, Bakker B, van Huet RAC, Ten Dam-van Loon NH, Thiadens AAHJ, Meester-Smoor MA, de Jong-Hesse Y, Los LI, den Hollander AI, Boon CJF, Kiemeney LA, van Eijk KR, Bakker MK, Hoyng CB, Kuiper JJW. de Groot EL, et al. Among authors: hiddingh s. JAMA Ophthalmol. 2023 Aug 1;141(8):737-745. doi: 10.1001/jamaophthalmol.2023.2557. JAMA Ophthalmol. 2023. PMID: 37410486 Free PMC article.
Nuclear Receptor Subfamily 4A Signaling as a Key Disease Pathway of CD1c+ Dendritic Cell Dysregulation in Systemic Sclerosis.
Servaas NH, Hiddingh S, Chouri E, Wichers CGK, Affandi AJ, Ottria A, Bekker CPJ, Cossu M, Silva-Cardoso SC, van der Kroef M, Hinrichs AC, Carvalheiro T, Vazirpanah N, Beretta L, Rossato M, Bonte-Mineur F, Radstake TRDJ, Kuiper JJW, Boes M, Pandit A. Servaas NH, et al. Among authors: hiddingh s. Arthritis Rheumatol. 2023 Feb;75(2):279-292. doi: 10.1002/art.42319. Epub 2022 Dec 8. Arthritis Rheumatol. 2023. PMID: 36482877 Free PMC article.
A Network of Serum Proteins Predict the Need for Systemic Immunomodulatory Therapy at Diagnosis in Noninfectious Uveitis.
Kuiper JJW, Verhagen FH, Hiddingh S, Wennink RAW, Hansen AM, Casey KA, Hoefer IE, Haitjema S, Drylewicz J, Yakin M, Sen HN, Radstake TRDJ, de Boer JH. Kuiper JJW, et al. Among authors: hiddingh s. Ophthalmol Sci. 2022 May 31;2(3):100175. doi: 10.1016/j.xops.2022.100175. eCollection 2022 Sep. Ophthalmol Sci. 2022. PMID: 36245752 Free PMC article.
Signaling by the inhibitory receptor CD200R is rewired by type I interferon.
van der Vlist M, Ramos MIP, van den Hoogen LL, Hiddingh S, Timmerman LM, de Hond TAP, Kaan ED, van der Kroef M, Lebbink RJ, Peters FMA, Khoury-Hanold W, Fritsch-Stork R, Radstake TRDJ, Meyaard L. van der Vlist M, et al. Among authors: hiddingh s. Sci Signal. 2021 Oct 12;14(704):eabb4324. doi: 10.1126/scisignal.abb4324. Epub 2021 Oct 12. Sci Signal. 2021. PMID: 34637328
ERAP2 Increases the Abundance of a Peptide Submotif Highly Selective for the Birdshot Uveitis-Associated HLA-A29.
Venema WJ, Hiddingh S, de Boer JH, Claas FHJ, Mulder A, den Hollander AI, Stratikos E, Sarkizova S, van der Veken LT, Janssen GMC, van Veelen PA, Kuiper JJW. Venema WJ, et al. Among authors: hiddingh s. Front Immunol. 2021 Feb 25;12:634441. doi: 10.3389/fimmu.2021.634441. eCollection 2021. Front Immunol. 2021. PMID: 33717175 Free PMC article.
22 results