Lim YH - Search Results

1

Site-selective chlorination of pyrrolic heterocycles by flavin dependent enzyme PrnC.

Peh G, Tay T, Tan LL, Tiong E, Bi J, Goh YL, Ye S, Lin F, Tan CJX, Tan YZ, Wong J, Zhao H, Wong FT, Ang EL, Lim YH. Peh G, et al. Among authors: lim yh. Commun Chem. 2024 Jan 5;7(1):7. doi: 10.1038/s42004-023-01083-1. Commun Chem. 2024. PMID: 38182798 Free PMC article.

2

Directed Evolution of a Fluorinase for Improved Fluorination Efficiency with a Non-native Substrate.

Sun H, Yeo WL, Lim YH, Chew X, Smith DJ, Xue B, Chan KP, Robinson RC, Robins EG, Zhao H, Ang EL. Sun H, et al. Among authors: lim yh. Angew Chem Int Ed Engl. 2016 Nov 7;55(46):14277-14280. doi: 10.1002/anie.201606722. Epub 2016 Oct 14. Angew Chem Int Ed Engl. 2016. PMID: 27739177

3

Probing the molecular determinants of fluorinase specificity.

Yeo WL, Chew X, Smith DJ, Chan KP, Sun H, Zhao H, Lim YH, Ang EL. Yeo WL, et al. Among authors: lim yh. Chem Commun (Camb). 2017 Feb 23;53(17):2559-2562. doi: 10.1039/c6cc09213f. Chem Commun (Camb). 2017. PMID: 28184383

4

CRISPR-Cas9 strategy for activation of silent Streptomyces biosynthetic gene clusters.

Zhang MM, Wong FT, Wang Y, Luo S, Lim YH, Heng E, Yeo WL, Cobb RE, Enghiad B, Ang EL, Zhao H. Zhang MM, et al. Among authors: lim yh. Nat Chem Biol. 2017 Apr 10:10.1038/nchembio.2341. doi: 10.1038/nchembio.2341. Online ahead of print. Nat Chem Biol. 2017. PMID: 28398287 Free PMC article.

5

Auroramycin: A Potent Antibiotic from Streptomyces roseosporus by CRISPR-Cas9 Activation.

Lim YH, Wong FT, Yeo WL, Ching KC, Lim YW, Heng E, Chen S, Tsai DJ, Lauderdale TL, Shia KS, Ho YS, Hoon S, Ang EL, Zhang MM, Zhao H. Lim YH, et al. Among authors: lim yw. Chembiochem. 2018 May 25. doi: 10.1002/cbic.201800266. Online ahead of print. Chembiochem. 2018. PMID: 29799651

6

Characterization of Cas proteins for CRISPR-Cas editing in streptomycetes.

Yeo WL, Heng E, Tan LL, Lim YW, Lim YH, Hoon S, Zhao H, Zhang MM, Wong FT. Yeo WL, et al. Among authors: lim yh, lim yw. Biotechnol Bioeng. 2019 Sep;116(9):2330-2338. doi: 10.1002/bit.27021. Epub 2019 May 30. Biotechnol Bioeng. 2019. PMID: 31090220

7

Chemogenomic profiling in yeast reveals antifungal mode-of-action of polyene macrolactam auroramycin.

Wong JH, Alfatah M, Kong KW, Hoon S, Yeo WL, Ching KC, Jie Hui Goh C, Zhang MM, Lim YH, Wong FT, Arumugam P. Wong JH, et al. Among authors: lim yh. PLoS One. 2019 Jun 10;14(6):e0218189. doi: 10.1371/journal.pone.0218189. eCollection 2019. PLoS One. 2019. PMID: 31181115 Free PMC article.

8

Biosynthetic engineering of the antifungal, anti-MRSA auroramycin.

Yeo WL, Heng E, Tan LL, Lim YW, Ching KC, Tsai DJ, Jhang YW, Lauderdale TL, Shia KS, Zhao H, Ang EL, Zhang MM, Lim YH, Wong FT. Yeo WL, et al. Among authors: lim yh, lim yw. Microb Cell Fact. 2020 Jan 6;19(1):3. doi: 10.1186/s12934-019-1274-y. Microb Cell Fact. 2020. PMID: 31906943 Free PMC article.

9

A Spirobicyclo[3.1.0]Terpene from the Investigation of Sesquiterpene Synthases from Lactarius deliciosus.

Cheong CB, Peh G, Wei Y, T R, Ang EL, Zhao H, Zhang C, Lim YH. Cheong CB, et al. Among authors: lim yh. ACS Chem Biol. 2023 Jan 20;18(1):134-140. doi: 10.1021/acschembio.2c00760. Epub 2023 Jan 3. ACS Chem Biol. 2023. PMID: 36594743

10

Cost-effective hybrid long-short read assembly delineates alternative GC-rich Streptomyces hosts for natural product discovery.

Heng E, Tan LL, Tay DWP, Lim YH, Yang LK, Seow DCS, Leong CY, Ng V, Ng SB, Kanagasundaram Y, Wong FT, Koduru L. Heng E, et al. Among authors: lim yh. Synth Syst Biotechnol. 2023 Mar 10;8(2):253-261. doi: 10.1016/j.synbio.2023.03.001. eCollection 2023 Jun. Synth Syst Biotechnol. 2023. PMID: 37007277 Free PMC article.

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