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A unique binding mode of P1' Leu-containing target sequences for Streptococcus pyogenes sortase A results in alternative cleavage.
RSC Chem Biol. 2023 Oct 18;5(1):30-40. doi: 10.1039/d3cb00129f. eCollection 2024 Jan 3.
RSC Chem Biol. 2023.
PMID: 38179192
Free PMC article.
Structures of Streptococcus pyogenes class A sortase in complex with substrate and product mimics provide key details of target recognition.
Johnson DA, Piper IM, Vogel BA, Jackson SN, Svendsen JE, Kodama HM, Lee DE, Lindblom KM, McCarty J, Antos JM, Amacher JF.
Johnson DA, et al. Among authors: kodama hm.
J Biol Chem. 2022 Oct;298(10):102446. doi: 10.1016/j.jbc.2022.102446. Epub 2022 Aug 31.
J Biol Chem. 2022.
PMID: 36055407
Free PMC article.
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Sequence variation in the β7-β8 loop of bacterial class A sortase enzymes alters substrate selectivity.
Piper IM, Struyvenberg SA, Valgardson JD, Johnson DA, Gao M, Johnston K, Svendsen JE, Kodama HM, Hvorecny KL, Antos JM, Amacher JF.
Piper IM, et al. Among authors: kodama hm.
J Biol Chem. 2021 Aug;297(2):100981. doi: 10.1016/j.jbc.2021.100981. Epub 2021 Jul 22.
J Biol Chem. 2021.
PMID: 34302812
Free PMC article.
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Structural and biochemical analyses of selectivity determinants in chimeric Streptococcus Class A sortase enzymes.
Gao M, Johnson DA, Piper IM, Kodama HM, Svendsen JE, Tahti E, Longshore-Neate F, Vogel B, Antos JM, Amacher JF.
Gao M, et al. Among authors: kodama hm.
Protein Sci. 2022 Mar;31(3):701-715. doi: 10.1002/pro.4266. Epub 2022 Jan 3.
Protein Sci. 2022.
PMID: 34939250
Free PMC article.
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