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FGFR3 overactivation in the brain is responsible for memory impairments in Crouzon syndrome mouse model.
Cornille M, Moriceau S, Khonsari RH, Heuzé Y, Loisay L, Boitez V, Morice A, Arnaud E, Collet C, Bensidhoum M, Kaci N, Boddaert N, Paternoster G, Rauschendorfer T, Werner S, Mansour SL, Di Rocco F, Oury F, Legeai-Mallet L. Cornille M, et al. Among authors: loisay l. J Exp Med. 2022 Apr 4;219(4):e20201879. doi: 10.1084/jem.20201879. Epub 2022 Mar 7. J Exp Med. 2022. PMID: 35254402 Free PMC article.
Theobroma cacao improves bone growth by modulating defective ciliogenesis in a mouse model of achondroplasia.
Martin L, Kaci N, Benoist-Lasselin C, Mondoloni M, Decaudaveine S, Estibals V, Cornille M, Loisay L, Flipo J, Demuynck B, de la Luz Cádiz-Gurrea M, Barbault F, Fernández-Arroyo S, Schibler L, Segura-Carretero A, Dambroise E, Legeai-Mallet L. Martin L, et al. Among authors: loisay l. Bone Res. 2022 Jan 25;10(1):8. doi: 10.1038/s41413-021-00177-7. Bone Res. 2022. PMID: 35078974 Free PMC article.
Phosphatase inhibition by LB-100 enhances BMN-111 stimulation of bone growth.
Shuhaibar LC, Kaci N, Egbert JR, Horville T, Loisay L, Vigone G, Uliasz TF, Dambroise E, Swingle MR, Honkanen RE, Biosse Duplan M, Jaffe LA, Legeai-Mallet L. Shuhaibar LC, et al. Among authors: loisay l. JCI Insight. 2021 May 10;6(9):e141426. doi: 10.1172/jci.insight.141426. JCI Insight. 2021. PMID: 33986191 Free PMC article.