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Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma.
Mol Cell. 2024 Jan 18;84(2):261-276.e18. doi: 10.1016/j.molcel.2023.12.003. Epub 2024 Jan 3.
Mol Cell. 2024.
PMID: 38176414
Free article.
Translational readthrough of nonsense mutant TP53 by mRNA incorporation of 5-Fluorouridine.
Palomar-Siles M, Heldin A, Zhang M, Strandgren C, Yurevych V, van Dinter JT, Engels SAG, Hofman DA, Öhlin S, Meineke B, Bykov VJN, van Heesch S, Wiman KG.
Palomar-Siles M, et al. Among authors: engels sag.
Cell Death Dis. 2022 Nov 25;13(11):997. doi: 10.1038/s41419-022-05431-2.
Cell Death Dis. 2022.
PMID: 36433934
Free PMC article.
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Epigenetic modulation of neuroblastoma enhances T cell and NK cell immunogenicity by inducing a tumor-cell lineage switch.
Cornel AM, Dunnebach E, Hofman DA, Das S, Sengupta S, van den Ham F, Wienke J, Strijker JGM, van den Beemt DAMH, Essing AHW, Koopmans B, Engels SAG, Lo Presti V, Szanto CS, George RE, Molenaar JJ, van Heesch S, Dierselhuis MP, Nierkens S.
Cornel AM, et al. Among authors: engels sag.
J Immunother Cancer. 2022 Dec;10(12):e005002. doi: 10.1136/jitc-2022-005002.
J Immunother Cancer. 2022.
PMID: 36521927
Free PMC article.
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Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma.
Hofman DA, Ruiz-Orera J, Yannuzzi I, Murugesan R, Brown A, Clauser KR, Condurat AL, van Dinter JT, Engels SAG, Goodale A, van der Lugt J, Abid T, Wang L, Zhou KN, Vogelzang J, Ligon KL, Phoenix TN, Roth JA, Root DE, Hubner N, Golub TR, Bandopadhayay P, van Heesch S, Prensner JR.
Hofman DA, et al. Among authors: engels sag.
bioRxiv [Preprint]. 2023 May 6:2023.05.04.539399. doi: 10.1101/2023.05.04.539399.
bioRxiv. 2023.
PMID: 37205492
Free PMC article.
Updated.
Preprint.
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The Neo-Open Reading Frame Peptides That Comprise the Tumor Framome Are a Rich Source of Neoantigens for Cancer Immunotherapy.
Martin MV, Aguilar-Rosas S, Franke K, Pieterse M, Langelaar JV, Schreurs R, Bijlsma MF, Besselink MG, Koster J, Timens W, Khasraw M, Ashley DM, Keir ST, Ottensmeier CH, King EV, Verheij J, Waasdorp C, Valk PJM, Engels SAG, Oostenbach E, van Dinter JT, Hofman DA, Mok JY, van Esch WJE, Wilmink H, Monkhorst K, Verheul HMW, Poel D, Hiltermann TJN, Kempen LCLTV, Groen HJM, Aerts JGJV, Heesch SV, Löwenberg B, Plasterk R, Kloosterman WP.
Martin MV, et al. Among authors: engels sag.
Cancer Immunol Res. 2024 Jun 4;12(6):759-778. doi: 10.1158/2326-6066.CIR-23-0158.
Cancer Immunol Res. 2024.
PMID: 38573707
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EWSR1-WT1 Target Genes and Therapeutic Options Identified in a Novel DSRCT In Vitro Model.
Bleijs M, Pleijte C, Engels S, Ringnalda F, Meyer-Wentrup F, van de Wetering M, Clevers H.
Bleijs M, et al.
Cancers (Basel). 2021 Dec 2;13(23):6072. doi: 10.3390/cancers13236072.
Cancers (Basel). 2021.
PMID: 34885181
Free PMC article.
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DRAM1 Promotes Lysosomal Delivery of Mycobacterium marinum in Macrophages.
Banducci-Karp A, Xie J, Engels SAG, Sarantaris C, van Hage P, Varela M, Meijer AH, van der Vaart M.
Banducci-Karp A, et al. Among authors: engels sag.
Cells. 2023 Mar 7;12(6):828. doi: 10.3390/cells12060828.
Cells. 2023.
PMID: 36980169
Free PMC article.
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