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Hedgehog signaling is a promising target for the treatment of hepatic fibrogenesis: a new management strategy using itraconazole-loaded nanoparticles.
Elmorsy EA, Saber S, Kira AY, Alghasham A, Abdel-Hamed MR, Amer MM, Mohamed EA, AlSalloom A A, Alkhamiss AS, Hamad RS, Abdel-Reheim MA, Ellethy AT, Elsisi HA, Alsharidah M, Elghandour SR, Elnawawy T, Abdelhady R. Elmorsy EA, et al. Front Pharmacol. 2024 May 14;15:1377980. doi: 10.3389/fphar.2024.1377980. eCollection 2024. Front Pharmacol. 2024. PMID: 38808257 Free PMC article.
A novel combination therapy targets sonic hedgehog signaling by the dual inhibition of HMG-CoA reductase and HSP90 in rats with non-alcoholic steatohepatitis.
Mohammed OA, Youssef ME, Doghish AS, Hamad RS, Abdel-Reheim MA, Alghamdi M, Alamri MMS, Alfaifi J, Adam MIE, Alharthi MH, Alhalafi AH, Bahashwan E, Rezigalla AA, BinAfif DF, Abdel-Ghany S, Attia MA, Elmorsy EA, Al-Noshokaty TM, Fikry H, Saleh LA, Saber S. Mohammed OA, et al. Among authors: elmorsy ea. Eur J Pharm Sci. 2024 May 5;198:106792. doi: 10.1016/j.ejps.2024.106792. Online ahead of print. Eur J Pharm Sci. 2024. PMID: 38714237 Free article.
Orexins in apoptosis: a dual regulatory role.
Cavalu S, Saber S, Hamad RS, Abdel-Reheim MA, Elmorsy EA, Youssef ME. Cavalu S, et al. Among authors: elmorsy ea. Front Cell Neurosci. 2024 Apr 12;18:1336145. doi: 10.3389/fncel.2024.1336145. eCollection 2024. Front Cell Neurosci. 2024. PMID: 38699177 Free PMC article. Review.
Corrigendum: Unveiling the therapeutic potential of exogenous β-hydroxybutyrate for chronic colitis in rats: novel insights on autophagy, apoptosis, and pyroptosis.
Abdelhady R, Saber S, Abdel-Reheim MA, Mohammad S Alamri M, Alfaifi J, Adam MIE, Saleh LA, Farag AI, Elmorsy EA, El-Wakeel HS, Doghish AS, Shaker ME, Hazem SH, Ramadan HA, Hamad RS, Mohammed OA. Abdelhady R, et al. Among authors: elmorsy ea. Front Pharmacol. 2024 Mar 13;15:1382529. doi: 10.3389/fphar.2024.1382529. eCollection 2024. Front Pharmacol. 2024. PMID: 38545556 Free PMC article.
The role of matrix metalloproteinase-2 and miR-196a2 in bronchial asthma pathogenesis and diagnosis.
Mohammed OA, Doghish AS, Alamri MMS, Alharthi MH, Alfaifi J, Adam MIE, Alhalafi AH, AlQahtani AAJ, Rezigalla AA, Taura MG, Isa AI, Binafif AF, Attia MA, Elmorsy EA, Yousef AA, Abdel-Reheim MA, Elkady MA. Mohammed OA, et al. Among authors: elmorsy ea. Heliyon. 2024 Mar 12;10(6):e27694. doi: 10.1016/j.heliyon.2024.e27694. eCollection 2024 Mar 30. Heliyon. 2024. PMID: 38509956 Free PMC article.
Linagliptin, a DPP-4 inhibitor, activates AMPK/FOXO3a and suppresses NFκB to mitigate the debilitating effects of diethylnitrosamine exposure in rat liver: Novel mechanistic insights.
Abdelhady R, Mohammed OA, Doghish AS, Hamad RS, Abdel-Reheim MA, Alamri MMS, Alharthi MH, Alfaifi J, Adam MIE, Alhalafi AH, Mohammed NA, Isa AI, Abdel-Ghany S, Attia MA, Elmorsy EA, Al-Noshokaty TM, Nomier Y, El-Dakroury WA, Saber S. Abdelhady R, et al. Among authors: elmorsy ea. FASEB J. 2024 Feb 29;38(4):e23480. doi: 10.1096/fj.202302461RR. FASEB J. 2024. PMID: 38354025
Itraconazole halts hepatocellular carcinoma progression by modulating sonic hedgehog signaling in rats: A novel therapeutic approach.
Mohammed OA, Doghish AS, Saleh LA, Alghamdi M, Alamri MMS, Alfaifi J, Adam MIE, Alharthi MH, Alshahrani AM, Alhalafi AH, BinAfif WF, Rezigalla AA, Abdel-Reheim MA, El-Wakeel HS, Attia MA, Elmorsy EA, Al-Noshokaty TM, Nomier Y, Saber S. Mohammed OA, et al. Among authors: elmorsy ea. Pathol Res Pract. 2024 Jan;253:155086. doi: 10.1016/j.prp.2023.155086. Epub 2024 Jan 3. Pathol Res Pract. 2024. PMID: 38176308
Alvespimycin Exhibits Potential Anti-TGF-β Signaling in the Setting of a Proteasome Activator in Rats with Bleomycin-Induced Pulmonary Fibrosis: A Promising Novel Approach.
Mohammed OA, Abdel-Reheim MA, Saleh LA, Alamri MMS, Alfaifi J, Adam MIE, Farrag AA, AlQahtani AAJ, BinAfif WF, Hashish AA, Abdel-Ghany S, Elmorsy EA, El-Wakeel HS, Doghish AS, Hamad RS, Saber S. Mohammed OA, et al. Among authors: elmorsy ea. Pharmaceuticals (Basel). 2023 Aug 9;16(8):1123. doi: 10.3390/ph16081123. Pharmaceuticals (Basel). 2023. PMID: 37631038 Free PMC article.
12 results