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Expanding a precision medicine platform for malignant peripheral nerve sheath tumors: New patient-derived orthotopic xenografts, cell lines and tumor entities.
Creus-Bachiller E, Fernández-Rodríguez J, Magallón-Lorenz M, Ortega-Bertran S, Navas-Rutete S, Romagosa C, Silva TM, Pané M, Estival A, Perez Sidelnikova D, Morell M, Mazuelas H, Carrió M, Lausová T, Reuss D, Gel B, Villanueva A, Serra E, Lázaro C. Creus-Bachiller E, et al. Among authors: magallon lorenz m. Mol Oncol. 2024 Apr;18(4):895-917. doi: 10.1002/1878-0261.13534. Epub 2023 Oct 20. Mol Oncol. 2024. PMID: 37798904 Free PMC article.
Generation of human iPSC-derived neurofibromaspheres for in vitro and in vivo uses.
Mazuelas H, Uriarte-Arrazola I, Fernández-Rodríguez J, Magallón-Lorenz M, Villanueva A, Lázaro C, Gel B, Serra E, Carrió M. Mazuelas H, et al. Among authors: magallon lorenz m. STAR Protoc. 2023 Mar 27;4(2):102198. doi: 10.1016/j.xpro.2023.102198. Online ahead of print. STAR Protoc. 2023. PMID: 36976677 Free PMC article.
Deep genomic analysis of malignant peripheral nerve sheath tumor cell lines challenges current malignant peripheral nerve sheath tumor diagnosis.
Magallón-Lorenz M, Terribas E, Ortega-Bertran S, Creus-Bachiller E, Fernández M, Requena G, Rosas I, Mazuelas H, Uriarte-Arrazola I, Negro A, Lausová T, Castellanos E, Blanco I, DeVries G, Kawashima H, Legius E, Brems H, Mautner V, Kluwe L, Ratner N, Wallace M, Fernández-Rodriguez J, Lázaro C, Fletcher JA, Reuss D, Carrió M, Gel B, Serra E. Magallón-Lorenz M, et al. iScience. 2023 Jan 31;26(2):106096. doi: 10.1016/j.isci.2023.106096. eCollection 2023 Feb 17. iScience. 2023. PMID: 36818284 Free PMC article.
Modeling iPSC-derived human neurofibroma-like tumors in mice uncovers the heterogeneity of Schwann cells within plexiform neurofibromas.
Mazuelas H, Magallón-Lorenz M, Fernández-Rodríguez J, Uriarte-Arrazola I, Richaud-Patin Y, Terribas E, Villanueva A, Castellanos E, Blanco I, Raya Á, Chojnacki J, Heyn H, Romagosa C, Lázaro C, Gel B, Carrió M, Serra E. Mazuelas H, et al. Among authors: magallon lorenz m. Cell Rep. 2022 Feb 15;38(7):110385. doi: 10.1016/j.celrep.2022.110385. Cell Rep. 2022. PMID: 35172160 Free article.
Chromosomal translocations inactivating CDKN2A support a single path for malignant peripheral nerve sheath tumor initiation.
Magallón-Lorenz M, Fernández-Rodríguez J, Terribas E, Creus-Batchiller E, Romagosa C, Estival A, Perez Sidelnikova D, Salvador H, Villanueva A, Blanco I, Carrió M, Lázaro C, Serra E, Gel B. Magallón-Lorenz M, et al. Hum Genet. 2021 Aug;140(8):1241-1252. doi: 10.1007/s00439-021-02296-x. Epub 2021 May 31. Hum Genet. 2021. PMID: 34059954
The IL-2RG R328X nonsense mutation allows partial STAT-5 phosphorylation and defines a critical region involved in the leaky-SCID phenotype.
Arcas-García A, Garcia-Prat M, Magallón-Lorenz M, Martín-Nalda A, Drechsel O, Ossowski S, Alonso L, Rivière JG, Soler-Palacín P, Colobran R, Sayós J, Martínez-Gallo M, Franco-Jarava C. Arcas-García A, et al. Among authors: magallon lorenz m. Clin Exp Immunol. 2020 Apr;200(1):61-72. doi: 10.1111/cei.13405. Epub 2020 Jan 19. Clin Exp Immunol. 2020. PMID: 31799703 Free PMC article.
Effect of Specific Mutations in Cd300 Complexes Formation; Potential Implication of Cd300f in Multiple Sclerosis.
Martínez-Barriocanal Á, Arcas-García A, Magallon-Lorenz M, Ejarque-Ortíz A, Negro-Demontel ML, Comas-Casellas E, Schwartz S Jr, Malhotra S, Montalban X, Peluffo H, Martín M, Comabella M, Sayós J. Martínez-Barriocanal Á, et al. Among authors: magallon lorenz m. Sci Rep. 2017 Oct 19;7(1):13544. doi: 10.1038/s41598-017-12881-8. Sci Rep. 2017. PMID: 29051512 Free PMC article.