Saeed A - Search Results

1

Novel pyrazoline linked acyl thiourea pharmacophores as antimicrobial, urease, amylase and α-glucosidase inhibitors: design, synthesis, SAR and molecular docking studies.

Saeed A, Ahmed A, Haider MB, Ismail H, Hayat K, Shabir G, El-Seedi HR. Saeed A, et al. RSC Adv. 2024 Jan 2;14(2):1018-1033. doi: 10.1039/d3ra06812a. eCollection 2024 Jan 2. RSC Adv. 2024. PMID: 38174269 Free PMC article.

2

Novel adamantyl clubbed iminothiazolidinones as promising elastase inhibitors: design, synthesis, molecular docking, ADMET and DFT studies.

Ahmed A, Saeed A, Ejaz SA, Aziz M, Hashmi MZ, Channar PA, Abbas Q, Raza H, Shafiq Z, El-Seedi HR. Ahmed A, et al. Among authors: saeed a. RSC Adv. 2022 Apr 19;12(19):11974-11991. doi: 10.1039/d1ra09318e. eCollection 2022 Apr 13. RSC Adv. 2022. PMID: 35481107 Free PMC article.

3

Synthesis of amantadine clubbed N-aryl amino thiazoles as potent urease, α-amylase & α-glucosidase inhibitors, kinetic and molecular docking studies.

Zahra FT, Saeed A, Ahmed A, Ismail H, Ijaz MU, Albericio F. Zahra FT, et al. Among authors: saeed a. RSC Adv. 2023 Aug 22;13(36):24988-25001. doi: 10.1039/d3ra05330j. eCollection 2023 Aug 21. RSC Adv. 2023. PMID: 37614781 Free PMC article.

4

Drug-1,3,4-Thiadiazole Conjugates as Novel Mixed-Type Inhibitors of Acetylcholinesterase: Synthesis, Molecular Docking, Pharmacokinetics, and ADMET Evaluation.

Ujan R, Saeed A, Channar PA, Larik FA, Abbas Q, Alajmi MF, El-Seedi HR, Rind MA, Hassan M, Raza H, Seo SY. Ujan R, et al. Among authors: saeed a. Molecules. 2019 Feb 28;24(5):860. doi: 10.3390/molecules24050860. Molecules. 2019. PMID: 30823444 Free PMC article.

5

Novel C-2 Symmetric Molecules as α-Glucosidase and α-Amylase Inhibitors: Design, Synthesis, Kinetic Evaluation, Molecular Docking and Pharmacokinetics.

Shahzad D, Saeed A, Larik FA, Channar PA, Abbas Q, Alajmi MF, Arshad MI, Erben MF, Hassan M, Raza H, Seo SY, El-Seedi HR. Shahzad D, et al. Among authors: saeed a. Molecules. 2019 Apr 17;24(8):1511. doi: 10.3390/molecules24081511. Molecules. 2019. PMID: 30999646 Free PMC article.

6

Synthesis, molecular docking and kinetic studies of novel quinolinyl based acyl thioureas as mushroom tyrosinase inhibitors and free radical scavengers.

Mustafa MN, Saeed A, Channar PA, Larik FA, Zain-Ul Abideen M, Shabir G, Abbas Q, Hassan M, Raza H, Seo SY. Mustafa MN, et al. Among authors: saeed a. Bioorg Chem. 2019 Sep;90:103063. doi: 10.1016/j.bioorg.2019.103063. Epub 2019 Jun 12. Bioorg Chem. 2019. PMID: 31220666

7

Identification of novel C-2 symmetric Bis-Azo-Azamethine molecules as competitive inhibitors of mushroom tyrosinase and free radical scavengers: synthesis, kinetics, and molecular docking studies.

Saeed A, Ahmed A, Ali Channar P, Shabir G, Hassan A, Zia-Ur-Rehman, Abbas Q, Hassan M, Raza H, Seo SY, El-Seedi HR. Saeed A, et al. J Biomol Struct Dyn. 2022 Jul;40(10):4419-4428. doi: 10.1080/07391102.2020.1857841. Epub 2020 Dec 20. J Biomol Struct Dyn. 2022. PMID: 33342351

8

Synthesis, X-ray, Hirshfeld surface analysis, exploration of DNA binding, urease enzyme inhibition and anticancer activities of novel adamantane-naphthyl thiourea conjugate.

Arshad N, Saeed A, Perveen F, Ujan R, Farooqi SI, Ali Channar P, Shabir G, El-Seedi HR, Javed A, Yamin M, Bolte M, Hökelek T. Arshad N, et al. Among authors: saeed a. Bioorg Chem. 2021 Apr;109:104707. doi: 10.1016/j.bioorg.2021.104707. Epub 2021 Feb 9. Bioorg Chem. 2021. PMID: 33639362

9

Synthesis of novel hybrid pharmacophore of N-((4-sulfamoylphenyl)carbamothioyl)alkanamides as potent carbonic anhydrase-II and 15-lipoxygenase inhibitors.

Saeed A, Khan SU, Saeed M, Shabir G, Hasan A, Khera RA, El-Seedi H, Halim SA, Khan A, Al-Harrasi A, Iqbal J. Saeed A, et al. Among authors: saeed m. Drug Dev Res. 2022 May;83(3):745-754. doi: 10.1002/ddr.21906. Epub 2021 Dec 12. Drug Dev Res. 2022. PMID: 34897776

10

Metal nanoparticles fabricated by green chemistry using natural extracts: biosynthesis, mechanisms, and applications.

El-Seedi HR, El-Shabasy RM, Khalifa SAM, Saeed A, Shah A, Shah R, Iftikhar FJ, Abdel-Daim MM, Omri A, Hajrahand NH, Sabir JSM, Zou X, Halabi MF, Sarhan W, Guo W. El-Seedi HR, et al. Among authors: saeed a. RSC Adv. 2019 Aug 8;9(42):24539-24559. doi: 10.1039/c9ra02225b. eCollection 2019 Aug 2. RSC Adv. 2019. PMID: 35527869 Free PMC article. Review.

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