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Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy.
Hu J, Dziumbla S, Lin J, Bibli SI, Zukunft S, de Mos J, Awwad K, Frömel T, Jungmann A, Devraj K, Cheng Z, Wang L, Fauser S, Eberhart CG, Sodhi A, Hammock BD, Liebner S, Müller OJ, Glaubitz C, Hammes HP, Popp R, Fleming I. Hu J, et al. Nature. 2017 Dec 14;552(7684):248-252. doi: 10.1038/nature25013. Epub 2017 Dec 6. Nature. 2017. PMID: 29211719 Free PMC article.
Cystathionine γ Lyase Sulfhydrates the RNA Binding Protein Human Antigen R to Preserve Endothelial Cell Function and Delay Atherogenesis.
Bibli SI, Hu J, Sigala F, Wittig I, Heidler J, Zukunft S, Tsilimigras DI, Randriamboavonjy V, Wittig J, Kojonazarov B, Schürmann C, Siragusa M, Siuda D, Luck B, Abdel Malik R, Filis KA, Zografos G, Chen C, Wang DW, Pfeilschifter J, Brandes RP, Szabo C, Papapetropoulos A, Fleming I. Bibli SI, et al. Among authors: hu j. Circulation. 2019 Jan 2;139(1):101-114. doi: 10.1161/CIRCULATIONAHA.118.034757. Circulation. 2019. PMID: 29970364 Free article.
Shear stress regulates cystathionine γ lyase expression to preserve endothelial redox balance and reduce membrane lipid peroxidation.
Bibli SI, Hu J, Leisegang MS, Wittig J, Zukunft S, Kapasakalidi A, Fisslthaler B, Tsilimigras D, Zografos G, Filis K, Brandes RP, Papapetropoulos A, Sigala F, Fleming I. Bibli SI, et al. Among authors: hu j. Redox Biol. 2020 Jan;28:101379. doi: 10.1016/j.redox.2019.101379. Epub 2019 Nov 13. Redox Biol. 2020. PMID: 31759247 Free PMC article.
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