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The murine retinal pigment epithelium requires peroxisomal β-oxidation to maintain lysosomal function and prevent dedifferentiation.
Kocherlakota S, Das Y, Swinkels D, Vanmunster M, Callens M, Vinckier S, Vaz FM, Sinha D, Van Veldhoven PP, Fransen M, Baes M. Kocherlakota S, et al. Among authors: van veldhoven pp. Proc Natl Acad Sci U S A. 2023 Oct 24;120(43):e2301733120. doi: 10.1073/pnas.2301733120. Epub 2023 Oct 20. Proc Natl Acad Sci U S A. 2023. PMID: 37862382 Free PMC article.
RABENOSYN separation-of-function mutations uncouple endosomal recycling from lysosomal degradation, causing a distinct Mendelian disorder.
Paul F, Ng C, Mohamad Sahari UB, Nafissi S, Nilipoor Y, Tavasoli AR, Bonnard C, Wong PM, Nabavizadeh N, Altunoğlu U, Estiar MA, Majoie CB, Lee H, Nelson SF, Gan-Or Z, Rouleau GA, Van Veldhoven PP, Massie R, Hennekam RC, Kariminejad A, Reversade B. Paul F, et al. Among authors: van veldhoven pp. Hum Mol Genet. 2022 Oct 28;31(21):3729-3740. doi: 10.1093/hmg/ddac120. Hum Mol Genet. 2022. PMID: 35652444
Peroxisome-Derived Hydrogen Peroxide Modulates the Sulfenylation Profiles of Key Redox Signaling Proteins in Flp-In T-REx 293 Cells.
Lismont C, Revenco I, Li H, Costa CF, Lenaerts L, Hussein MAF, De Bie J, Knoops B, Van Veldhoven PP, Derua R, Fransen M. Lismont C, et al. Among authors: van veldhoven pp. Front Cell Dev Biol. 2022 Apr 26;10:888873. doi: 10.3389/fcell.2022.888873. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 35557958 Free PMC article.
Nuclear Sphingosine-1-phosphate Lyase Generated ∆2-hexadecenal is A Regulator of HDAC Activity and Chromatin Remodeling in Lung Epithelial Cells.
Ebenezer DL, Ramchandran R, Fu P, Mangio LA, Suryadevara V, Ha AW, Berdyshev E, Van Veldhoven PP, Kron SJ, Schumacher F, Kleuser B, Natarajan V. Ebenezer DL, et al. Among authors: van veldhoven pp. Cell Biochem Biophys. 2021 Sep;79(3):575-592. doi: 10.1007/s12013-021-01005-9. Epub 2021 Jun 3. Cell Biochem Biophys. 2021. PMID: 34085165 Free PMC article.
Peroxisomal Multifunctional Protein 2 Deficiency Perturbs Lipid Homeostasis in the Retina and Causes Visual Dysfunction in Mice.
Das Y, Swinkels D, Kocherlakota S, Vinckier S, Vaz FM, Wever E, van Kampen AHC, Jun B, Do KV, Moons L, Bazan NG, Van Veldhoven PP, Baes M. Das Y, et al. Among authors: van veldhoven pp. Front Cell Dev Biol. 2021 Feb 2;9:632930. doi: 10.3389/fcell.2021.632930. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 33604342 Free PMC article.
257 results