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Radiosynthesis and whole-body distribution in mice of a 18 F-labeled azepino[4,3-b]indole-1-one derivative with multimodal activity for the treatment of Alzheimer's disease.
Lee SH, Purgatorio R, Samarelli F, Catto M, Denora N, Morgese MG, Tucci P, Trabace L, Kim HW, Park HS, Kim SE, Lee BC, de Candia M, Altomare CD. Lee SH, et al. Among authors: de candia m. Arch Pharm (Weinheim). 2024 Mar;357(3):e2300491. doi: 10.1002/ardp.202300491. Epub 2023 Dec 29. Arch Pharm (Weinheim). 2024. PMID: 38158335
Novel factor Xa inhibitors: a patent review.
de Candia M, Lopopolo G, Altomare C. de Candia M, et al. Expert Opin Ther Pat. 2009 Nov;19(11):1535-80. doi: 10.1517/13543770903270532. Expert Opin Ther Pat. 2009. PMID: 19743898 Review.
2-Benzazepine nitrones protect dopaminergic neurons against 6-hydroxydopamine-induced oxidative toxicity.
Soto-Otero R, Méndez-Álvarez E, Sánchez-Iglesias S, Labandeira-García JL, Rodríguez-Pallares J, Zubkov FI, Zaytsev VP, Voskressensky LG, Varlamov AV, de Candia M, Fiorella F, Altomare C. Soto-Otero R, et al. Among authors: de candia m. Arch Pharm (Weinheim). 2012 Aug;345(8):598-609. doi: 10.1002/ardp.201200007. Epub 2012 Apr 25. Arch Pharm (Weinheim). 2012. PMID: 22532340
Protein crystallography and fragment-based drug design.
Caliandro R, Belviso DB, Aresta BM, de Candia M, Altomare CD. Caliandro R, et al. Among authors: de candia m. Future Med Chem. 2013 Jun;5(10):1121-40. doi: 10.4155/fmc.13.84. Future Med Chem. 2013. PMID: 23795969 Review.
How a β-D-glucoside side chain enhances binding affinity to thrombin of inhibitors bearing 2-chlorothiophene as P1 moiety: crystallography, fragment deconstruction study, and evaluation of antithrombotic properties.
Belviso BD, Caliandro R, de Candia M, Zaetta G, Lopopolo G, Incampo F, Colucci M, Altomare CD. Belviso BD, et al. Among authors: de candia m. J Med Chem. 2014 Oct 23;57(20):8563-75. doi: 10.1021/jm5010754. Epub 2014 Oct 14. J Med Chem. 2014. PMID: 25268757
88 results