Purgatorio R - Search Results

1

Radiosynthesis and whole-body distribution in mice of a ¹⁸ F-labeled azepino[4,3-b]indole-1-one derivative with multimodal activity for the treatment of Alzheimer's disease.

Lee SH, Purgatorio R, Samarelli F, Catto M, Denora N, Morgese MG, Tucci P, Trabace L, Kim HW, Park HS, Kim SE, Lee BC, de Candia M, Altomare CD. Lee SH, et al. Among authors: purgatorio r. Arch Pharm (Weinheim). 2024 Mar;357(3):e2300491. doi: 10.1002/ardp.202300491. Epub 2023 Dec 29. Arch Pharm (Weinheim). 2024. PMID: 38158335

2

Novel bisphosphonates with antiresorptive effect in bone mineralization and osteoclastogenesis.

Savino S, Toscano A, Purgatorio R, Profilo E, Laghezza A, Tortorella P, Angelelli M, Cellamare S, Scala R, Tricarico D, Marobbio CMT, Perna F, Vitale P, Agamennone M, Dimiccoli V, Tolomeo A, Scilimati A. Savino S, et al. Among authors: purgatorio r. Eur J Med Chem. 2018 Oct 5;158:184-200. doi: 10.1016/j.ejmech.2018.08.044. Epub 2018 Aug 18. Eur J Med Chem. 2018. PMID: 30216851

3

Design, synthesis and biological evaluation of indane-2-arylhydrazinylmethylene-1,3-diones and indol-2-aryldiazenylmethylene-3-ones as beta-amyloid aggregation inhibitors.

Catto M, Aliano R, Carotti A, Cellamare S, Palluotto F, Purgatorio R, De Stradis A, Campagna F. Catto M, et al. Among authors: purgatorio r. Eur J Med Chem. 2010 Apr;45(4):1359-66. doi: 10.1016/j.ejmech.2009.12.029. Epub 2009 Dec 23. Eur J Med Chem. 2010. PMID: 20137834

4

Synthesis and biophysical evaluation of arylhydrazono-1H-2-indolinones as β-amyloid aggregation inhibitors.

Campagna F, Catto M, Purgatorio R, Altomare CD, Carotti A, De Stradis A, Palazzo G. Campagna F, et al. Among authors: purgatorio r. Eur J Med Chem. 2011 Jan;46(1):275-84. doi: 10.1016/j.ejmech.2010.11.015. Epub 2010 Nov 18. Eur J Med Chem. 2011. PMID: 21144622

5

Investigation on the influence of (Z)-3-(2-(3-chlorophenyl)hydrazono)-5,6-dihydroxyindolin-2-one (PT2) on β-amyloid(1-40) aggregation and toxicity.

Catto M, Arnesano F, Palazzo G, De Stradis A, Calò V, Losacco M, Purgatorio R, Campagna F. Catto M, et al. Among authors: purgatorio r. Arch Biochem Biophys. 2014 Oct 15;560:73-82. doi: 10.1016/j.abb.2014.07.015. Epub 2014 Jul 19. Arch Biochem Biophys. 2014. PMID: 25051344

6

A New Class of 1-Aryl-5,6-dihydropyrrolo[2,1-a]isoquinoline Derivatives as Reversers of P-Glycoprotein-Mediated Multidrug Resistance in Tumor Cells.

Nevskaya AA, Matveeva MD, Borisova TN, Niso M, Colabufo NA, Boccarelli A, Purgatorio R, de Candia M, Cellamare S, Voskressensky LG, Altomare CD. Nevskaya AA, et al. Among authors: purgatorio r. ChemMedChem. 2018 Aug 10;13(15):1588-1596. doi: 10.1002/cmdc.201800177. Epub 2018 Jul 4. ChemMedChem. 2018. PMID: 29802687

7

Insights into Structure-Activity Relationships of 3-Arylhydrazonoindolin-2-One Derivatives for Their Multitarget Activity on β-Amyloid Aggregation and Neurotoxicity.

Purgatorio R, de Candia M, De Palma A, De Santis F, Pisani L, Campagna F, Cellamare S, Altomare CD, Catto M. Purgatorio R, et al. Molecules. 2018 Jun 26;23(7):1544. doi: 10.3390/molecules23071544. Molecules. 2018. PMID: 29949947 Free PMC article.

8

Investigating 1,2,3,4,5,6-hexahydroazepino[4,3-b]indole as scaffold of butyrylcholinesterase-selective inhibitors with additional neuroprotective activities for Alzheimer's disease.

Purgatorio R, de Candia M, Catto M, Carrieri A, Pisani L, De Palma A, Toma M, Ivanova OA, Voskressensky LG, Altomare CD. Purgatorio R, et al. Eur J Med Chem. 2019 Sep 1;177:414-424. doi: 10.1016/j.ejmech.2019.05.062. Epub 2019 May 28. Eur J Med Chem. 2019. PMID: 31158754

9

Pyrrolo[2,1-a]isoquinoline scaffold in drug discovery: advances in synthesis and medicinal chemistry.

Matveeva MD, Purgatorio R, Voskressensky LG, Altomare CD. Matveeva MD, et al. Among authors: purgatorio r. Future Med Chem. 2019 Oct;11(20):2735-2755. doi: 10.4155/fmc-2019-0136. Epub 2019 Sep 26. Future Med Chem. 2019. PMID: 31556691 Review.

10

A Prospective Repurposing of Dantrolene as a Multitarget Agent for Alzheimer's Disease.

Bolognino I, Giangregorio N, Pisani L, de Candia M, Purgatorio R, Tonazzi A, Altomare CD, Cellamare S, Catto M. Bolognino I, et al. Among authors: purgatorio r. Molecules. 2019 Nov 25;24(23):4298. doi: 10.3390/molecules24234298. Molecules. 2019. PMID: 31775359 Free PMC article.

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