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Studies of antibacterial activity (in vitro and in vivo) and mode of action for des-acyl tridecaptins (DATs).
Couturier C, Ronzon Q, Lattanzi G, Lingard I, Coyne S, Cazals V, Dubarry N, Yvon S, Leroi-Geissler C, Gracia OR, Teague J, Sordello S, Corbett D, Bauch C, Monlong C, Payne L, Taillier T, Fuchs H, Broenstrup M, Harrison PH, Moynié L, Lakshminarayanan A, Gianga TM, Hussain R, Naismith JH, Mourez M, Bacqué E, Björkling F, Sabuco JF, Franzyk H. Couturier C, et al. Among authors: dubarry n. Eur J Med Chem. 2024 Feb 5;265:116097. doi: 10.1016/j.ejmech.2023.116097. Epub 2023 Dec 23. Eur J Med Chem. 2024. PMID: 38157595
Optimization of the Antibacterial Spectrum and the Developability Profile of the Novel-Class Natural Product Corramycin.
Renard S, Versluys S, Taillier T, Dubarry N, Leroi-Geissler C, Rey A, Cornaire E, Sordello S, Carry JB, Angouillant-Boniface O, Gouyon T, Thompson F, Lebourg G, Certal V, Balazs L, Arranz E, Doerflinger G, Bretin F, Gervat V, Brohan E, Kraft V, Boulenc X, Ducelier C, Bacqué E, Couturier C. Renard S, et al. Among authors: dubarry n. J Med Chem. 2023 Dec 28;66(24):16869-16887. doi: 10.1021/acs.jmedchem.3c01564. Epub 2023 Dec 13. J Med Chem. 2023. PMID: 38088830
Structure Elucidation, Total Synthesis, Antibacterial In Vivo Efficacy and Biosynthesis Proposal of Myxobacterial Corramycin.
Couturier C, Groß S, von Tesmar A, Hoffmann J, Deckarm S, Fievet A, Dubarry N, Taillier T, Pöverlein C, Stump H, Kurz M, Toti L, Haag Richter S, Schummer D, Sizun P, Hoffmann M, Prasad Awal R, Zaburannyi N, Harmrolfs K, Wink J, Lessoud E, Vermat T, Cazals V, Silve S, Bauer A, Mourez M, Fraisse L, Leroi-Geissler C, Rey A, Versluys S, Bacqué E, Müller R, Renard S. Couturier C, et al. Among authors: dubarry n. Angew Chem Int Ed Engl. 2022 Dec 19;61(51):e202210747. doi: 10.1002/anie.202210747. Epub 2022 Nov 21. Angew Chem Int Ed Engl. 2022. PMID: 36197755 Free PMC article.
RocS drives chromosome segregation and nucleoid protection in Streptococcus pneumoniae.
Mercy C, Ducret A, Slager J, Lavergne JP, Freton C, Nagarajan SN, Garcia PS, Noirot-Gros MF, Dubarry N, Nourikyan J, Veening JW, Grangeasse C. Mercy C, et al. Among authors: dubarry n. Nat Microbiol. 2019 Oct;4(10):1661-1670. doi: 10.1038/s41564-019-0472-z. Epub 2019 Jun 10. Nat Microbiol. 2019. PMID: 31182798 Free PMC article.
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