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B56δ long-disordered arms form a dynamic PP2A regulation interface coupled with global allostery and Jordan's syndrome mutations.
Wu CG, Balakrishnan VK, Merrill RA, Parihar PS, Konovolov K, Chen YC, Xu Z, Wei H, Sundaresan R, Cui Q, Wadzinski BE, Swingle MR, Musiyenko A, Chung WK, Honkanen RE, Suzuki A, Huang X, Strack S, Xing Y. Wu CG, et al. Among authors: xing y. Proc Natl Acad Sci U S A. 2024 Jan 2;121(1):e2310727120. doi: 10.1073/pnas.2310727120. Epub 2023 Dec 27. Proc Natl Acad Sci U S A. 2024. PMID: 38150499 Free PMC article.
Extended regulation interface coupled to the allosteric network and disease mutations in the PP2A-B56δ holoenzyme.
Wu CG, Balakrishnan VK, Parihar PS, Konovolov K, Chen YC, Merrill RA, Wei H, Carragher B, Sundaresan R, Cui Q, Wadzinski BE, Swingle MR, Musiyenko A, Honkanen R, Chung WK, Suzuki A, Strack S, Huang X, Xing Y. Wu CG, et al. Among authors: xing y. bioRxiv [Preprint]. 2023 Apr 5:2023.03.09.530109. doi: 10.1101/2023.03.09.530109. bioRxiv. 2023. PMID: 37066309 Free PMC article. Preprint.
Structural basis of protein phosphatase 2A stable latency.
Jiang L, Stanevich V, Satyshur KA, Kong M, Watkins GR, Wadzinski BE, Sengupta R, Xing Y. Jiang L, et al. Among authors: xing y. Nat Commun. 2013;4:1699. doi: 10.1038/ncomms2663. Nat Commun. 2013. PMID: 23591866 Free PMC article.
Methylation-regulated decommissioning of multimeric PP2A complexes.
Wu CG, Zheng A, Jiang L, Rowse M, Stanevich V, Chen H, Li Y, Satyshur KA, Johnson B, Gu TJ, Liu Z, Xing Y. Wu CG, et al. Among authors: xing y. Nat Commun. 2017 Dec 22;8(1):2272. doi: 10.1038/s41467-017-02405-3. Nat Commun. 2017. PMID: 29273778 Free PMC article.
Structure of the protein phosphatase 2A holoenzyme.
Xu Y, Xing Y, Chen Y, Chao Y, Lin Z, Fan E, Yu JW, Strack S, Jeffrey PD, Shi Y. Xu Y, et al. Among authors: xing y. Cell. 2006 Dec 15;127(6):1239-51. doi: 10.1016/j.cell.2006.11.033. Cell. 2006. PMID: 17174897 Free article.
PP2A-B' holoenzyme substrate recognition, regulation and role in cytokinesis.
Wu CG, Chen H, Guo F, Yadav VK, Mcilwain SJ, Rowse M, Choudhary A, Lin Z, Li Y, Gu T, Zheng A, Xu Q, Lee W, Resch E, Johnson B, Day J, Ge Y, Ong IM, Burkard ME, Ivarsson Y, Xing Y. Wu CG, et al. Among authors: xing y. Cell Discov. 2017 Aug 8;3:17027. doi: 10.1038/celldisc.2017.27. eCollection 2017. Cell Discov. 2017. PMID: 28884018 Free PMC article.
6,068 results