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A computational method for predicting the most likely evolutionary trajectories in the stepwise accumulation of resistance mutations.
Elife. 2023 Dec 22;12:e84756. doi: 10.7554/eLife.84756.
Elife. 2023.
PMID: 38132182
Free PMC article.
Selection for cooperativity causes epistasis predominately between native contacts and enables epistasis-based structure reconstruction.
Eccleston RC, Pollock DD, Goldstein RA.
Eccleston RC, et al.
Proc Natl Acad Sci U S A. 2021 Apr 20;118(16):e2010057118. doi: 10.1073/pnas.2010057118.
Proc Natl Acad Sci U S A. 2021.
PMID: 33879570
Free PMC article.
Item in Clipboard
A Mechanistic Model for Predicting Cell Surface Presentation of Competing Peptides by MHC Class I Molecules.
Boulanger DSM, Eccleston RC, Phillips A, Coveney PV, Elliott T, Dalchau N.
Boulanger DSM, et al. Among authors: eccleston rc.
Front Immunol. 2018 Jul 5;9:1538. doi: 10.3389/fimmu.2018.01538. eCollection 2018.
Front Immunol. 2018.
PMID: 30026743
Free PMC article.
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Host genotype and time dependent antigen presentation of viral peptides: predictions from theory.
Eccleston RC, Coveney PV, Dalchau N.
Eccleston RC, et al.
Sci Rep. 2017 Oct 30;7(1):14367. doi: 10.1038/s41598-017-14415-8.
Sci Rep. 2017.
PMID: 29084996
Free PMC article.
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The Role of Multiscale Protein Dynamics in Antigen Presentation and T Lymphocyte Recognition.
Eccleston RC, Wan S, Dalchau N, Coveney PV.
Eccleston RC, et al.
Front Immunol. 2017 Jul 10;8:797. doi: 10.3389/fimmu.2017.00797. eCollection 2017.
Front Immunol. 2017.
PMID: 28740497
Free PMC article.
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Effects of rotational symmetry breaking in polymer-coated nanopores.
Osmanović D, Kerr-Winter M, Eccleston RC, Hoogenboom BW, Ford IJ.
Osmanović D, et al. Among authors: eccleston rc.
J Chem Phys. 2015 Jan 21;142(3):034901. doi: 10.1063/1.4905719.
J Chem Phys. 2015.
PMID: 25612727
Free article.
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