Wright N - Search Results

1

Essential role of obscurin kinase-1 in cardiomyocyte coupling via N-cadherin phosphorylation.

Wang L, Tsakiroglou P, Gonzales R, Cho S, Li A, Dos Remedios C, Wright N, Kontrogianni-Konstantopoulos A. Wang L, et al. Among authors: wright n. JCI Insight. 2024 Feb 8;9(3):e162178. doi: 10.1172/jci.insight.162178. JCI Insight. 2024. PMID: 38127465 Free PMC article.

2

Deregulated Ca²⁺ cycling underlies the development of arrhythmia and heart disease due to mutant obscurin.

Hu LR, Ackermann MA, Hecker PA, Prosser BL, King B, O'Connell KA, Grogan A, Meyer LC, Berndsen CE, Wright NT, Jonathan Lederer W, Kontrogianni-Konstantopoulos A. Hu LR, et al. Sci Adv. 2017 Jun 7;3(6):e1603081. doi: 10.1126/sciadv.1603081. eCollection 2017 Jun. Sci Adv. 2017. PMID: 28630914 Free PMC article.

3

Novel obscurins mediate cardiomyocyte adhesion and size via the PI3K/AKT/mTOR signaling pathway.

Ackermann MA, King B, Lieberman NAP, Bobbili PJ, Rudloff M, Berndsen CE, Wright NT, Hecker PA, Kontrogianni-Konstantopoulos A. Ackermann MA, et al. J Mol Cell Cardiol. 2017 Oct;111:27-39. doi: 10.1016/j.yjmcc.2017.08.004. Epub 2017 Aug 4. J Mol Cell Cardiol. 2017. PMID: 28826662 Free PMC article.

4

Novel mutations in MYBPC1 are associated with myogenic tremor and mild myopathy.

Stavusis J, Lace B, Schäfer J, Geist J, Inashkina I, Kidere D, Pajusalu S, Wright NT, Saak A, Weinhold M, Haubenberger D, Jackson S, Kontrogianni-Konstantopoulos A, Bönnemann CG. Stavusis J, et al. Ann Neurol. 2019 Jul;86(1):129-142. doi: 10.1002/ana.25494. Epub 2019 May 17. Ann Neurol. 2019. PMID: 31025394 Free PMC article.

5

Heterozygous variants in MYBPC1 are associated with an expanded neuromuscular phenotype beyond arthrogryposis.

Shashi V, Geist J, Lee Y, Yoo Y, Shin U, Schoch K, Sullivan J, Stong N, Smith E, Jasien J, Kranz P; Undiagnosed Diseases Network; Lee Y, Shin YB, Wright NT, Choi M, Kontrogianni-Konstantopoulos A. Shashi V, et al. Among authors: wright nt. Hum Mutat. 2019 Aug;40(8):1115-1126. doi: 10.1002/humu.23760. Epub 2019 May 5. Hum Mutat. 2019. PMID: 31264822 Free PMC article.

6

Structural Insights on the Obscurin-Binding Domains in Titin.

Letourneau AG, Wright NT. Letourneau AG, et al. Protein Pept Lett. 2018;25(11):973-979. doi: 10.2174/0929866525666181004102031. Protein Pept Lett. 2018. PMID: 30289063

7

Obscurin is a semi-flexible molecule in solution.

Whitley JA, Ex-Willey AM, Marzolf DR, Ackermann MA, Tongen AL, Kokhan O, Wright NT. Whitley JA, et al. Protein Sci. 2019 Apr;28(4):717-726. doi: 10.1002/pro.3578. Epub 2019 Feb 6. Protein Sci. 2019. PMID: 30666746 Free PMC article.

8

Chemical shift assignments for the Ig2 domain of human obscurin A.

Temple JE, Oehler MC, Wright NT. Temple JE, et al. Biomol NMR Assign. 2016 Apr;10(1):63-5. doi: 10.1007/s12104-015-9638-7. Epub 2015 Sep 15. Biomol NMR Assign. 2016. PMID: 26373426

9

Mechanical dissociation of the M-band titin/obscurin complex is directionally dependent.

Caldwell TA, Sumner I, Wright NT. Caldwell TA, et al. FEBS Lett. 2015 Jul 8;589(15):1735-9. doi: 10.1016/j.febslet.2015.05.023. Epub 2015 May 19. FEBS Lett. 2015. PMID: 26001486 Free article.

10

Structure of giant muscle proteins.

Meyer LC, Wright NT. Meyer LC, et al. Front Physiol. 2013 Dec 12;4:368. doi: 10.3389/fphys.2013.00368. Front Physiol. 2013. PMID: 24376425 Free PMC article. Review.

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