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Distribution of ubiquilin 2 and TDP-43 aggregates throughout the CNS in UBQLN2 p.T487I-linked amyotrophic lateral sclerosis and frontotemporal dementia.
Nementzik LR, Thumbadoo KM, Murray HC, Gordon D, Yang S, Blair IP, Turner C, Faull RLM, Curtis MA, McLean C, Nicholson GA, Swanson MEV, Scotter EL. Nementzik LR, et al. Among authors: curtis ma. Brain Pathol. 2024 May;34(3):e13230. doi: 10.1111/bpa.13230. Epub 2023 Dec 19. Brain Pathol. 2024. PMID: 38115557 Free PMC article.
Hippocampal aggregation signatures of pathogenic UBQLN2 in amyotrophic lateral sclerosis and frontotemporal dementia.
Thumbadoo KM, Dieriks BV, Murray HC, Swanson MEV, Yoo JH, Mehrabi NF, Turner C, Dragunow M, Faull RLM, Curtis MA, Siddique T, Shaw CE, Newell KL, Henden L, Williams KL, Nicholson GA, Scotter EL. Thumbadoo KM, et al. Among authors: curtis ma. Brain. 2024 May 4:awae140. doi: 10.1093/brain/awae140. Online ahead of print. Brain. 2024. PMID: 38703371
A transient protein folding response targets aggregation in the early phase of TDP-43-mediated neurodegeneration.
San Gil R, Pascovici D, Venturato J, Brown-Wright H, Mehta P, Madrid San Martin L, Wu J, Luan W, Chui YK, Bademosi AT, Swaminathan S, Naidoo S, Berning BA, Wright AL, Keating SS, Curtis MA, Faull RLM, Lee JD, Ngo ST, Lee A, Morsch M, Chung RS, Scotter E, Lisowski L, Mirzaei M, Walker AK. San Gil R, et al. Among authors: curtis ma. Nat Commun. 2024 Feb 19;15(1):1508. doi: 10.1038/s41467-024-45646-9. Nat Commun. 2024. PMID: 38374041 Free PMC article.
362 results