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Interpretation of in vitro concentration-response data for risk assessment and regulatory decision-making: Report from the 2022 IWGT quantitative analysis expert working group meeting.
Beal MA, Chen G, Dearfield KL, Gi M, Gollapudi B, Heflich RH, Horibata K, Long AS, Lovell DP, Parsons BL, Pfuhler S, Wills J, Zeller A, Johnson G, White PA. Beal MA, et al. Among authors: long as. Environ Mol Mutagen. 2023 Dec 19. doi: 10.1002/em.22582. Online ahead of print. Environ Mol Mutagen. 2023. PMID: 38115239 Review.
Establishing a quantitative framework for regulatory interpretation of genetic toxicity dose-response data: Margin of exposure case study of 48 compounds with both in vivo mutagenicity and carcinogenicity dose-response data.
Chepelev N, Long AS, Beal M, Barton-Maclaren T, Johnson G, Dearfield KL, Roberts DJ, van Benthem J, White P. Chepelev N, et al. Among authors: long as. Environ Mol Mutagen. 2023 Jan;64(1):4-15. doi: 10.1002/em.22517. Epub 2023 Jan 6. Environ Mol Mutagen. 2023. PMID: 36345771 Free PMC article.
Quantitative in vitro to in vivo extrapolation of genotoxicity data provides protective estimates of in vivo dose.
Beal MA, Audebert M, Barton-Maclaren T, Battaion H, Bemis JC, Cao X, Chen C, Dertinger SD, Froetschl R, Guo X, Johnson G, Hendriks G, Khoury L, Long AS, Pfuhler S, Settivari RS, Wickramasuriya S, White P. Beal MA, et al. Among authors: long as. Environ Mol Mutagen. 2023 Feb;64(2):105-122. doi: 10.1002/em.22521. Epub 2022 Dec 22. Environ Mol Mutagen. 2023. PMID: 36495195
A comparison of transgenic rodent mutation and in vivo comet assay responses for 91 chemicals.
Kirkland D, Levy DD, LeBaron MJ, Aardema MJ, Beevers C, Bhalli J, Douglas GR, Escobar PA, Farabaugh CS, Guerard M, Johnson GE, Kulkarni R, Le Curieux F, Long AS, Lott J, Lovell DP, Luijten M, Marchetti F, Nicolette JJ, Pfuhler S, Roberts DJ, Stankowski LF Jr, Thybaud V, Weiner SK, Williams A, Witt KL, Young R. Kirkland D, et al. Among authors: long as. Mutat Res Genet Toxicol Environ Mutagen. 2019 Mar;839:21-35. doi: 10.1016/j.mrgentox.2019.01.007. Epub 2019 Jan 18. Mutat Res Genet Toxicol Environ Mutagen. 2019. PMID: 30744809 Free PMC article.
66 results