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Impaired neuron differentiation in GBA-associated Parkinson's disease is linked to cell cycle defects in organoids.
Rosety I, Zagare A, Saraiva C, Nickels S, Antony P, Almeida C, Glaab E, Halder R, Velychko S, Rauen T, Schöler HR, Bolognin S, Sauter T, Jarazo J, Krüger R, Schwamborn JC. Rosety I, et al. Among authors: bolognin s. NPJ Parkinsons Dis. 2023 Dec 18;9(1):166. doi: 10.1038/s41531-023-00616-8. NPJ Parkinsons Dis. 2023. PMID: 38110400 Free PMC article.
Multiomics analysis identifies novel facilitators of human dopaminergic neuron differentiation.
Gomez Ramos B, Ohnmacht J, de Lange N, Valceschini E, Ginolhac A, Catillon M, Ferrante D, Rakovic A, Halder R, Massart F, Arena G, Antony P, Bolognin S, Klein C, Krause R, Schulz MH, Sauter T, Krüger R, Sinkkonen L. Gomez Ramos B, et al. Among authors: bolognin s. EMBO Rep. 2024 Jan;25(1):254-285. doi: 10.1038/s44319-023-00024-2. Epub 2023 Dec 19. EMBO Rep. 2024. PMID: 38177910 Free PMC article.
Targeting Human Endothelial Cells with Glutathione and Alanine Increases the Crossing of a Polypeptide Nanocarrier through a Blood-Brain Barrier Model and Entry to Human Brain Organoids.
Mészáros M, Phan THM, Vigh JP, Porkoláb G, Kocsis A, Páli EK, Polgár TF, Walter FR, Bolognin S, Schwamborn JC, Jan JS, Deli MA, Veszelka S. Mészáros M, et al. Among authors: bolognin s. Cells. 2023 Feb 3;12(3):503. doi: 10.3390/cells12030503. Cells. 2023. PMID: 36766845 Free PMC article.
Bone Tissue and the Nervous System: What Do They Have in Common?
Minoia A, Dalle Carbonare L, Schwamborn JC, Bolognin S, Valenti MT. Minoia A, et al. Among authors: bolognin s. Cells. 2022 Dec 22;12(1):51. doi: 10.3390/cells12010051. Cells. 2022. PMID: 36611845 Free PMC article. Review.
A Triple Combination of Targeting Ligands Increases the Penetration of Nanoparticles across a Blood-Brain Barrier Culture Model.
Veszelka S, Mészáros M, Porkoláb G, Szecskó A, Kondor N, Ferenc G, Polgár TF, Katona G, Kóta Z, Kelemen L, Páli T, Vigh JP, Walter FR, Bolognin S, Schwamborn JC, Jan JS, Deli MA. Veszelka S, et al. Among authors: bolognin s. Pharmaceutics. 2021 Dec 30;14(1):86. doi: 10.3390/pharmaceutics14010086. Pharmaceutics. 2021. PMID: 35056983 Free PMC article.
Structural Plasticity of Dopaminergic Neurons Requires the Activation of the D3R-nAChR Heteromer and the PI3K-ERK1/2/Akt-Induced Expression of c-Fos and p70S6K Signaling Pathway.
Mutti V, Bono F, Tomasoni Z, Bontempi L, Guglielmi A, Bolognin S, Schwamborn JC, Missale C, Fiorentini C. Mutti V, et al. Among authors: bolognin s. Mol Neurobiol. 2022 Apr;59(4):2129-2149. doi: 10.1007/s12035-022-02748-z. Epub 2022 Jan 19. Mol Neurobiol. 2022. PMID: 35044626 Free PMC article.
The Parkinson's-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1.
Walter J, Bolognin S, Poovathingal SK, Magni S, Gérard D, Antony PMA, Nickels SL, Salamanca L, Berger E, Smits LM, Grzyb K, Perfeito R, Hoel F, Qing X, Ohnmacht J, Bertacchi M, Jarazo J, Ignac T, Monzel AS, Gonzalez-Cano L, Krüger R, Sauter T, Studer M, de Almeida LP, Tronstad KJ, Sinkkonen L, Skupin A, Schwamborn JC. Walter J, et al. Among authors: bolognin s. Cell Rep. 2021 Oct 19;37(3):109864. doi: 10.1016/j.celrep.2021.109864. Cell Rep. 2021. PMID: 34686322 Free article.
Parkinson's Disease Phenotypes in Patient Neuronal Cultures and Brain Organoids Improved by 2-Hydroxypropyl-β-Cyclodextrin Treatment.
Jarazo J, Barmpa K, Modamio J, Saraiva C, Sabaté-Soler S, Rosety I, Griesbeck A, Skwirblies F, Zaffaroni G, Smits LM, Su J, Arias-Fuenzalida J, Walter J, Gomez-Giro G, Monzel AS, Qing X, Vitali A, Cruciani G, Boussaad I, Brunelli F, Jäger C, Rakovic A, Li W, Yuan L, Berger E, Arena G, Bolognin S, Schmidt R, Schröder C, Antony PMA, Klein C, Krüger R, Seibler P, Schwamborn JC. Jarazo J, et al. Among authors: bolognin s. Mov Disord. 2022 Jan;37(1):80-94. doi: 10.1002/mds.28810. Epub 2021 Oct 12. Mov Disord. 2022. PMID: 34637165 Free PMC article.
55 results