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Skull bone marrow channels as immune gateways to the central nervous system.
Mazzitelli JA, Pulous FE, Smyth LCD, Kaya Z, Rustenhoven J, Moskowitz MA, Kipnis J, Nahrendorf M. Mazzitelli JA, et al. Nat Neurosci. 2023 Dec;26(12):2052-2062. doi: 10.1038/s41593-023-01487-1. Epub 2023 Nov 23. Nat Neurosci. 2023. PMID: 37996526 Free PMC article. Review.
Identification of direct connections between the dura and the brain.
Smyth LCD, Xu D, Okar SV, Dykstra T, Rustenhoven J, Papadopoulos Z, Bhasiin K, Kim MW, Drieu A, Mamuladze T, Blackburn S, Gu X, Gaitán MI, Nair G, Storck SE, Du S, White MA, Bayguinov P, Smirnov I, Dikranian K, Reich DS, Kipnis J. Smyth LCD, et al. Nature. 2024 Mar;627(8002):165-173. doi: 10.1038/s41586-023-06993-7. Epub 2024 Feb 7. Nature. 2024. PMID: 38326613
DALT: the brain's border patrol.
Park JH, Alexander JF, Smyth LCD, Kipnis J. Park JH, et al. Among authors: smyth lcd. Cell Res. 2024 May 22. doi: 10.1038/s41422-024-00976-7. Online ahead of print. Cell Res. 2024. PMID: 38777860 No abstract available.
An inducible genetic tool to track and manipulate specific microglial states reveals their plasticity and roles in remyelination.
Barclay KM, Abduljawad N, Cheng Z, Kim MW, Zhou L, Yang J, Rustenhoven J, Mazzitelli JA, Smyth LCD, Kapadia D, Brioschi S, Beatty W, Hou J, Saligrama N, Colonna M, Yu G, Kipnis J, Li Q. Barclay KM, et al. Among authors: smyth lcd. Immunity. 2024 May 24:S1074-7613(24)00258-9. doi: 10.1016/j.immuni.2024.05.005. Online ahead of print. Immunity. 2024. PMID: 38821054 Free article.
Brain Pericytes As Mediators of Neuroinflammation.
Rustenhoven J, Jansson D, Smyth LC, Dragunow M. Rustenhoven J, et al. Trends Pharmacol Sci. 2017 Mar;38(3):291-304. doi: 10.1016/j.tips.2016.12.001. Epub 2016 Dec 22. Trends Pharmacol Sci. 2017. PMID: 28017362 Review.
Markers for human brain pericytes and smooth muscle cells.
Smyth LCD, Rustenhoven J, Scotter EL, Schweder P, Faull RLM, Park TIH, Dragunow M. Smyth LCD, et al. J Chem Neuroanat. 2018 Oct;92:48-60. doi: 10.1016/j.jchemneu.2018.06.001. Epub 2018 Jun 7. J Chem Neuroanat. 2018. PMID: 29885791
PU.1 regulates Alzheimer's disease-associated genes in primary human microglia.
Rustenhoven J, Smith AM, Smyth LC, Jansson D, Scotter EL, Swanson MEV, Aalderink M, Coppieters N, Narayan P, Handley R, Overall C, Park TIH, Schweder P, Heppner P, Curtis MA, Faull RLM, Dragunow M. Rustenhoven J, et al. Among authors: smyth lc. Mol Neurodegener. 2018 Aug 20;13(1):44. doi: 10.1186/s13024-018-0277-1. Mol Neurodegener. 2018. PMID: 30124174 Free PMC article.
330 results