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Epithelial talin-1 protects mice from citrobacter rodentium-induced colitis by restricting bacterial crypt intrusion and enhancing t cell immunity.
Latour YL, Allaman MM, Barry DP, Smith TM, Williams KJ, McNamara KM, Jacobse J, Goettel JA, Delgado AG, Piazuelo MB, Zhao S, Gobert AP, Wilson KT. Latour YL, et al. Among authors: williams kj. Gut Microbes. 2023 Jan-Dec;15(1):2192623. doi: 10.1080/19490976.2023.2192623. Gut Microbes. 2023. PMID: 36951501 Free PMC article.
The nutraceutical electrophile scavenger 2-hydroxybenzylamine (2-HOBA) attenuates gastric cancer development caused by Helicobacter pylori.
Gobert AP, Asim M, Smith TM, Williams KJ, Barry DP, Allaman MM, McNamara KM, Hawkins CV, Delgado AG, Blanca Piazuelo M, Rathmacher JA, Wilson KT. Gobert AP, et al. Among authors: williams kj. Biomed Pharmacother. 2023 Feb;158:114092. doi: 10.1016/j.biopha.2022.114092. Epub 2022 Dec 6. Biomed Pharmacother. 2023. PMID: 36493697 Free PMC article.
Electrophilic reactive aldehydes as a therapeutic target in colorectal cancer prevention and treatment.
Gobert AP, Asim M, Smith TM, Williams KJ, Barry DP, Allaman MM, McNamara KM, Hawkins CV, Delgado AG, Zhao S, Piazuelo MB, Washington MK, Coburn LA, Rathmacher JA, Wilson KT. Gobert AP, et al. Among authors: williams kj. Oncogene. 2023 May;42(20):1685-1691. doi: 10.1038/s41388-023-02691-w. Epub 2023 Apr 10. Oncogene. 2023. PMID: 37037901 Free PMC article.
Hypusination Maintains Intestinal Homeostasis and Prevents Colitis and Carcinogenesis by Enhancing Aldehyde Detoxification.
Gobert AP, Smith TM, Latour YL, Asim M, Barry DP, Allaman MM, Williams KJ, McNamara KM, Delgado AG, Short SP, Mirmira RG, Rose KL, Schey KL, Zagol-Ikapitte I, Coleman JS, Boutaud O, Zhao S, Piazuelo MB, Washington MK, Coburn LA, Wilson KT. Gobert AP, et al. Among authors: williams kj. Gastroenterology. 2023 Sep;165(3):656-669.e8. doi: 10.1053/j.gastro.2023.05.041. Epub 2023 Jun 2. Gastroenterology. 2023. PMID: 37271289
IL-4 Licenses B Cell Activation Through Cholesterol Synthesis.
Steach HR, York AG, Skadow MH, Chen S, Zhao J, Williams KJ, Zhou Q, Hsieh WY, Brewer JR, Qu R, Shyer JA, Harman C, Sefik E, Mowell WK, Bailis W, Cui C, Kluger Y, Bensinger SJ, Craft J, Flavell RA. Steach HR, et al. Among authors: williams kj. bioRxiv [Preprint]. 2024 May 15:2024.05.13.593964. doi: 10.1101/2024.05.13.593964. bioRxiv. 2024. PMID: 38798553 Free PMC article. Preprint.
IL-10 constrains sphingolipid metabolism to limit inflammation.
York AG, Skadow MH, Oh J, Qu R, Zhou QD, Hsieh WY, Mowel WK, Brewer JR, Kaffe E, Williams KJ, Kluger Y, Smale ST, Crawford JM, Bensinger SJ, Flavell RA. York AG, et al. Among authors: williams kj. Nature. 2024 Mar;627(8004):628-635. doi: 10.1038/s41586-024-07098-5. Epub 2024 Feb 21. Nature. 2024. PMID: 38383790 Free PMC article.
628 results