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Page 1
MYOD-SKP2 axis boosts tumorigenesis in fusion negative rhabdomyosarcoma by preventing differentiation through p57Kip2 targeting.
Pomella S, Cassandri M, D'Archivio L, Porrazzo A, Cossetti C, Phelps D, Perrone C, Pezzella M, Cardinale A, Wachtel M, Aloisi S, Milewski D, Colletti M, Sreenivas P, Walters ZS, Barillari G, Di Giannatale A, Milano GM, De Stefanis C, Alaggio R, Rodriguez-Rodriguez S, Carlesso N, Vakoc CR, Velardi E, Schafer BW, Guccione E, Gatz SA, Wasti A, Yohe M, Ignatius M, Quintarelli C, Shipley J, Miele L, Khan J, Houghton PJ, Marampon F, Gryder BE, De Angelis B, Locatelli F, Rota R. Pomella S, et al. Among authors: sreenivas p. Nat Commun. 2023 Dec 15;14(1):8373. doi: 10.1038/s41467-023-44130-0. Nat Commun. 2023. PMID: 38102140 Free PMC article.
The NOTCH1/SNAIL1/MEF2C Pathway Regulates Growth and Self-Renewal in Embryonal Rhabdomyosarcoma.
Ignatius MS, Hayes MN, Lobbardi R, Chen EY, McCarthy KM, Sreenivas P, Motala Z, Durbin AD, Molodtsov A, Reeder S, Jin A, Sindiri S, Beleyea BC, Bhere D, Alexander MS, Shah K, Keller C, Linardic CM, Nielsen PG, Malkin D, Khan J, Langenau DM. Ignatius MS, et al. Among authors: sreenivas p. Cell Rep. 2017 Jun 13;19(11):2304-2318. doi: 10.1016/j.celrep.2017.05.061. Cell Rep. 2017. PMID: 28614716 Free PMC article.
Interaction between SNAI2 and MYOD enhances oncogenesis and suppresses differentiation in Fusion Negative Rhabdomyosarcoma.
Pomella S, Sreenivas P, Gryder BE, Wang L, Milewski D, Cassandri M, Baxi K, Hensch NR, Carcarino E, Song Y, Chou HC, Yohe ME, Stanton BZ, Amadio B, Caruana I, De Stefanis C, De Vito R, Locatelli F, Chen Y, Chen EY, Houghton P, Khan J, Rota R, Ignatius MS. Pomella S, et al. Among authors: sreenivas p. Nat Commun. 2021 Jan 8;12(1):192. doi: 10.1038/s41467-020-20386-8. Nat Commun. 2021. PMID: 33420019 Free PMC article.
SNAI2-Mediated Repression of BIM Protects Rhabdomyosarcoma from Ionizing Radiation.
Wang L, Hensch NR, Bondra K, Sreenivas P, Zhao XR, Chen J, Moreno Campos R, Baxi K, Vaseva AV, Sunkel BD, Gryder BE, Pomella S, Stanton BZ, Zheng S, Chen EY, Rota R, Khan J, Houghton PJ, Ignatius MS. Wang L, et al. Among authors: sreenivas p. Cancer Res. 2021 Nov 1;81(21):5451-5463. doi: 10.1158/0008-5472.CAN-20-4191. Epub 2021 Aug 30. Cancer Res. 2021. PMID: 34462275 Free PMC article.
Defining function of wild-type and three patient-specific TP53 mutations in a zebrafish model of embryonal rhabdomyosarcoma.
Chen J, Baxi K, Lipsitt AE, Hensch NR, Wang L, Sreenivas P, Modi P, Zhao XR, Baudin A, Robledo DG, Bandyopadhyay A, Sugalski A, Challa AK, Kurmashev D, Gilbert AR, Tomlinson GE, Houghton P, Chen Y, Hayes MN, Chen EY, Libich DS, Ignatius MS. Chen J, et al. Among authors: sreenivas p. Elife. 2023 Jun 2;12:e68221. doi: 10.7554/eLife.68221. Elife. 2023. PMID: 37266578 Free PMC article.
The 3D chromatin landscape of rhabdomyosarcoma.
Wang M, Sreenivas P, Sunkel BD, Wang L, Ignatius M, Stanton BZ. Wang M, et al. Among authors: sreenivas p. NAR Cancer. 2023 Jun 13;5(3):zcad028. doi: 10.1093/narcan/zcad028. eCollection 2023 Sep. NAR Cancer. 2023. PMID: 37325549 Free PMC article.
A SNAI2/CTCF Interaction is Required for NOTCH1 Expression in Rhabdomyosarcoma.
Sreenivas P, Wang L, Wang M, Challa A, Modi P, Hensch NR, Gryder B, Chou HC, Zhao XR, Sunkel B, Moreno-Campos R, Khan J, Stanton BZ, Ignatius MS. Sreenivas P, et al. Mol Cell Biol. 2023;43(11):547-565. doi: 10.1080/10985549.2023.2256640. Epub 2023 Nov 17. Mol Cell Biol. 2023. PMID: 37882064 Free PMC article.
Ketogenic diet induces p53-dependent cellular senescence in multiple organs.
Wei SJ, Schell JR, Chocron ES, Varmazyad M, Xu G, Chen WH, Martinez GM, Dong FF, Sreenivas P, Trevino R Jr, Jiang H, Du Y, Saliba A, Qian W, Lorenzana B, Nazarullah A, Chang J, Sharma K, Munkácsy E, Horikoshi N, Gius D. Wei SJ, et al. Among authors: sreenivas p. Sci Adv. 2024 May 17;10(20):eado1463. doi: 10.1126/sciadv.ado1463. Epub 2024 May 17. Sci Adv. 2024. PMID: 38758782 Free PMC article.
Mitochondrial ACSS1-K635 acetylation knock-in mice exhibit altered metabolism, cell senescence, and nonalcoholic fatty liver disease.
Xu G, Quan S, Schell J, Gao Y, Varmazyad M, Sreenivas P, Cruz D, Jiang H, Pan M, Han X, Palavicini JP, Zhao P, Sun X, Marchant ED, Rasmussen BB, Li G, Katsumura S, Morita M, Munkácsy E, Horikoshi N, Chocron ES, Gius D. Xu G, et al. Among authors: sreenivas p. Sci Adv. 2024 May 17;10(20):eadj5942. doi: 10.1126/sciadv.adj5942. Epub 2024 May 17. Sci Adv. 2024. PMID: 38758779 Free PMC article.
18 results