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Type 2 diabetes impairs annulus fibrosus fiber deformation and rotation under disc compression in the University of California Davis type 2 diabetes mellitus (UCD-T2DM) rat model.
Rosenberg JL, Schaible E, Bostrom A, Lazar AA, Graham JL, Stanhope KL, Ritchie RO, Alliston TN, Lotz JC, Havel PJ, Acevedo C, Fields AJ. Rosenberg JL, et al. Among authors: ritchie ro. PNAS Nexus. 2023 Nov 3;2(12):pgad363. doi: 10.1093/pnasnexus/pgad363. eCollection 2023 Dec. PNAS Nexus. 2023. PMID: 38094616 Free PMC article.
TGF-beta regulates the mechanical properties and composition of bone matrix.
Balooch G, Balooch M, Nalla RK, Schilling S, Filvaroff EH, Marshall GW, Marshall SJ, Ritchie RO, Derynck R, Alliston T. Balooch G, et al. Among authors: ritchie ro. Proc Natl Acad Sci U S A. 2005 Dec 27;102(52):18813-8. doi: 10.1073/pnas.0507417102. Epub 2005 Dec 14. Proc Natl Acad Sci U S A. 2005. PMID: 16354837 Free PMC article.
Osteopontin deficiency increases bone fragility but preserves bone mass.
Thurner PJ, Chen CG, Ionova-Martin S, Sun L, Harman A, Porter A, Ager JW 3rd, Ritchie RO, Alliston T. Thurner PJ, et al. Among authors: ritchie ro. Bone. 2010 Jun;46(6):1564-73. doi: 10.1016/j.bone.2010.02.014. Epub 2010 Feb 18. Bone. 2010. PMID: 20171304 Free PMC article.
Tissue-specific calibration of extracellular matrix material properties by transforming growth factor-β and Runx2 in bone is required for hearing.
Chang JL, Brauer DS, Johnson J, Chen CG, Akil O, Balooch G, Humphrey MB, Chin EN, Porter AE, Butcher K, Ritchie RO, Schneider RA, Lalwani A, Derynck R, Marshall GW, Marshall SJ, Lustig L, Alliston T. Chang JL, et al. Among authors: ritchie ro. EMBO Rep. 2010 Oct;11(10):765-71. doi: 10.1038/embor.2010.135. Epub 2010 Sep 17. EMBO Rep. 2010. PMID: 20847738 Free PMC article.
221 results