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Advantages of evaluating γH2AX induction in non-clinical drug development.
Motoyama S, Takeiri A, Tanaka K, Harada A, Matsuzaki K, Taketo J, Matsuo S, Fujii E, Mishima M. Motoyama S, et al. Among authors: mishima m. Genes Environ. 2018 May 14;40:10. doi: 10.1186/s41021-018-0098-z. eCollection 2018. Genes Environ. 2018. PMID: 29785231 Free PMC article. Review.
Weight of evidence approach using a TK gene mutation assay with human TK6 cells for follow-up of positive results in Ames tests: a collaborative study by MMS/JEMS.
Yasui M, Fukuda T, Ukai A, Maniwa J, Imamura T, Hashizume T, Yamamoto H, Shibuya K, Narumi K, Fujiishi Y, Okada E, Fujishima S, Yamamoto M, Otani N, Nakamura M, Nishimura R, Ueda M, Mishima M, Matsuzaki K, Takeiri A, Tanaka K, Okada Y, Nakagawa M, Hamada S, Kajikawa A, Honda H, Adachi J, Misaki K, Ogawa K, Honma M. Yasui M, et al. Among authors: mishima m. Genes Environ. 2021 Mar 6;43(1):7. doi: 10.1186/s41021-021-00179-1. Genes Environ. 2021. PMID: 33676587 Free PMC article.
Rapid in vitro assessment of the immunogenicity potential of engineered antibody therapeutics through detection of CD4+ T cell interleukin-2 secretion.
Arata Y, Motoyama S, Yano M, Ikuno T, Ito S, Matsushita T, Takeiri A, Nishito Y, Yabuki N, Mizuno H, Sampei Z, Mishima M, Honda M, Kiyokawa J, Suzuki H, Chiba S, Tabo M, Kubo C. Arata Y, et al. Among authors: mishima m. MAbs. 2023 Jan-Dec;15(1):2253570. doi: 10.1080/19420862.2023.2253570. MAbs. 2023. PMID: 37682072 Free PMC article.
In vitro mammalian cell mutation assays based on transgenic reporters: A report of the International Workshop on Genotoxicity Testing (IWGT).
White PA, Luijten M, Mishima M, Cox JA, Hanna JN, Maertens RM, Zwart EP. White PA, et al. Among authors: mishima m. Mutat Res Genet Toxicol Environ Mutagen. 2019 Nov;847:403039. doi: 10.1016/j.mrgentox.2019.04.002. Epub 2019 Apr 13. Mutat Res Genet Toxicol Environ Mutagen. 2019. PMID: 31699347 Free article. Review.
878 results