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Methylation of histone H3 lysine 36 is a barrier for therapeutic interventions of head and neck squamous cell carcinoma.
Caeiro LD, Nakata Y, Borges RL, Garcia-Martinez L, Bañuelos CP, Stransky S, Chan HL, Brabson J, Domínguez D, Zhang Y, Lewis PW, Aznar-Benitah S, Cimmino L, Bilbao D, Sidoli S, Verdun RE, Morey L. Caeiro LD, et al. Among authors: chan hl. bioRxiv [Preprint]. 2023 Nov 6:2023.11.06.565847. doi: 10.1101/2023.11.06.565847. bioRxiv. 2023. PMID: 38076924 Free PMC article. Updated. Preprint.
Epigenetic mechanisms in breast cancer therapy and resistance.
Garcia-Martinez L, Zhang Y, Nakata Y, Chan HL, Morey L. Garcia-Martinez L, et al. Among authors: chan hl. Nat Commun. 2021 Mar 19;12(1):1786. doi: 10.1038/s41467-021-22024-3. Nat Commun. 2021. PMID: 33741974 Free PMC article. Review.
Endocrine resistance and breast cancer plasticity are controlled by CoREST.
Garcia-Martinez L, Adams AM, Chan HL, Nakata Y, Weich N, Stransky S, Zhang Z, Alshalalfa M, Sarria L, Mahal BA, Kesmodel SB, Celià-Terrassa T, Liu Z, Minucci S, Bilbao D, Sidoli S, Verdun RE, Morey L. Garcia-Martinez L, et al. Among authors: chan hl. Nat Struct Mol Biol. 2022 Nov;29(11):1122-1135. doi: 10.1038/s41594-022-00856-x. Epub 2022 Nov 7. Nat Struct Mol Biol. 2022. PMID: 36344844 Free PMC article.
Methylation of histone H3 lysine 36 is a barrier for therapeutic interventions of head and neck squamous cell carcinoma.
Caeiro LD, Nakata Y, Borges RL, Zha M, Garcia-Martinez L, Bañuelos CP, Stransky S, Liu T, Chan HL, Brabson J, Domínguez D, Zhang Y, Lewis PW, Aznar Benitah S, Cimmino L, Bilbao D, Sidoli S, Wang Z, Verdun RE, Morey L. Caeiro LD, et al. Among authors: chan hl. Genes Dev. 2024 Feb 13;38(1-2):46-69. doi: 10.1101/gad.351408.123. Genes Dev. 2024. PMID: 38286657
PDGFRA defines the mesenchymal stem cell Kaposi's sarcoma progenitors by enabling KSHV oncogenesis in an angiogenic environment.
Naipauer J, Rosario S, Gupta S, Premer C, Méndez-Solís O, Schlesinger M, Ponzinibbio V, Jain V, Gay L, Renne R, Chan HL, Morey L, Salyakina D, Abba M, Williams S, Hare JM, Goldschmidt-Clermont PJ, Mesri EA. Naipauer J, et al. Among authors: chan hl. PLoS Pathog. 2019 Dec 27;15(12):e1008221. doi: 10.1371/journal.ppat.1008221. eCollection 2019 Dec. PLoS Pathog. 2019. PMID: 31881074 Free PMC article.
p16 loss rescues functional decline of Brca1-deficient mammary stem cells.
Scott A, Bai F, Chan HL, Liu S, Slingerland JM, Robbins DJ, Capobianco AJ, Pei XH. Scott A, et al. Among authors: chan hl. Cell Cycle. 2017 Apr 18;16(8):759-764. doi: 10.1080/15384101.2017.1295185. Epub 2017 Feb 22. Cell Cycle. 2017. PMID: 28278054 Free PMC article.
p16INK4a suppresses BRCA1-deficient mammary tumorigenesis.
Scott A, Bai F, Chan HL, Liu S, Ma J, Slingerland JM, Robbins DJ, Capobianco AJ, Pei XH. Scott A, et al. Among authors: chan hl. Oncotarget. 2016 Dec 20;7(51):84496-84507. doi: 10.18632/oncotarget.13015. Oncotarget. 2016. PMID: 27811360 Free PMC article.
1,220 results