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Homeobox regulator Wilms Tumour 1 is displaced by androgen receptor at cis-regulatory elements in the endometrium of PCOS patients.
James DW, Quintela M, Lucini L, Alkafri NK, Healey GD, Younas K, Bunkheila A, Margarit L, Francis LW, Gonzalez D, Conlan RS. James DW, et al. Among authors: margarit l. Front Endocrinol (Lausanne). 2024 Apr 30;15:1368494. doi: 10.3389/fendo.2024.1368494. eCollection 2024. Front Endocrinol (Lausanne). 2024. PMID: 38745948 Free PMC article.
In silico enhancer mining reveals SNS-032 and EHMT2 inhibitors as therapeutic candidates in high-grade serous ovarian cancer.
Quintela M, James DW, Garcia J, Edwards K, Margarit L, Das N, Lutchman-Singh K, Beynon AL, Rioja I, Prinjha RK, Harker NR, Gonzalez D, Steven Conlan R, Francis LW. Quintela M, et al. Among authors: margarit l. Br J Cancer. 2023 Jul;129(1):163-174. doi: 10.1038/s41416-023-02274-2. Epub 2023 Apr 29. Br J Cancer. 2023. PMID: 37120667 Free PMC article.
Higher dose corticosteroids in patients admitted to hospital with COVID-19 who are hypoxic but not requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial.
RECOVERY Collaborative Group. Electronic address: recoverytrial@ndph.ox.ac.uk; RECOVERY Collaborative Group. RECOVERY Collaborative Group. Electronic address: recoverytrial@ndph.ox.ac.uk, et al. Lancet. 2023 May 6;401(10387):1499-1507. doi: 10.1016/S0140-6736(23)00510-X. Epub 2023 Apr 13. Lancet. 2023. PMID: 37060915 Free PMC article. Clinical Trial.
Bromodomain inhibitor i-BET858 triggers a unique transcriptional response coupled to enhanced DNA damage, cell cycle arrest and apoptosis in high-grade ovarian carcinoma cells.
Quintela M, James DW, Pociute A, Powell L, Edwards K, Coombes Z, Garcia J, Garton N, Das N, Lutchman-Singh K, Margarit L, Beynon AL, Rioja I, Prinjha RK, Harker NR, Gonzalez D, Conlan RS, Francis LW. Quintela M, et al. Among authors: margarit l. Clin Epigenetics. 2023 Apr 15;15(1):63. doi: 10.1186/s13148-023-01477-x. Clin Epigenetics. 2023. PMID: 37060086 Free PMC article.
WILL (When to Induce Labour to Limit risk in pregnancy hypertension): a multicentre randomised controlled trial - adaptations to deliver a timing-of-birth trial during the COVID-19 international pandemic.
Magee LA, Tohill S, Kirkham K, Evans R, Gkini E, Moakes CA, Stubbs C, Thornton J, von Dadelszen P; WILL Trial Study Group. Magee LA, et al. Trials. 2022 Oct 21;23(1):884. doi: 10.1186/s13063-022-06834-4. Trials. 2022. PMID: 36271441 Free PMC article. Clinical Trial.
Pregnancy and neonatal outcomes of COVID-19: The PAN-COVID study.
Mullins E, Perry A, Banerjee J, Townson J, Grozeva D, Milton R, Kirby N, Playle R, Bourne T, Lees C; PAN-COVID Investigators. Mullins E, et al. Eur J Obstet Gynecol Reprod Biol. 2022 Sep;276:161-167. doi: 10.1016/j.ejogrb.2022.07.010. Epub 2022 Jul 19. Eur J Obstet Gynecol Reprod Biol. 2022. PMID: 35914420 Free PMC article.
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