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In situ lipid-loading activates peripheral dendritic cell subsets characterized by cellular ROS accumulation but compromises their capacity to prime naïve T cells.
Christ A, Maas SL, Jin H, Lu C, Legein B, Wijnands E, Temmerman L, Otten J, Isaacs A, Zenke M, Stoll M, Biessen EAL, van der Vorst EPC. Christ A, et al. Among authors: zenke m. Free Radic Biol Med. 2024 Jan;210:406-415. doi: 10.1016/j.freeradbiomed.2023.11.044. Epub 2023 Dec 5. Free Radic Biol Med. 2024. PMID: 38061606 Free article.
The telomerase inhibitor imetelstat differentially targets JAK2V617F versus CALR mutant myeloproliferative neoplasm cells and inhibits JAK-STAT signaling.
Olschok K, Altenburg B, de Toledo MAS, Maurer A, Abels A, Beier F, Gezer D, Isfort S, Paeschke K, Brümmendorf TH, Zenke M, Chatain N, Koschmieder S. Olschok K, et al. Among authors: zenke m. Front Oncol. 2023 Oct 24;13:1277453. doi: 10.3389/fonc.2023.1277453. eCollection 2023. Front Oncol. 2023. PMID: 37941547 Free PMC article.
Guidelines for mouse and human DC generation.
Lutz MB, Ali S, Audiger C, Autenrieth SE, Berod L, Bigley V, Cyran L, Dalod M, Dörrie J, Dudziak D, Flórez-Grau G, Giusiano L, Godoy GJ, Heuer M, Krug AB, Lehmann CHK, Mayer CT, Naik SH, Scheu S, Schreibelt G, Segura E, Seré K, Sparwasser T, Tel J, Xu H, Zenke M. Lutz MB, et al. Among authors: zenke m. Eur J Immunol. 2023 Nov;53(11):e2249816. doi: 10.1002/eji.202249816. Epub 2022 Oct 27. Eur J Immunol. 2023. PMID: 36303448 Free PMC article.
Intrathymic dendritic cell-biased precursors promote human T cell lineage specification through IRF8-driven transmembrane TNF.
Liang KL, Roels J, Lavaert M, Putteman T, Boehme L, Tilleman L, Velghe I, Pegoretti V, Van de Walle I, Sontag S, Vandewalle J, Vandekerckhove B, Leclercq G, Van Vlierberghe P, Libert C, Van Nieuwerburgh F, Fischer R, Kontermann RE, Pfizenmaier K, Doody G, Zenke M, Taghon T. Liang KL, et al. Among authors: zenke m. Nat Immunol. 2023 Mar;24(3):474-486. doi: 10.1038/s41590-022-01417-6. Epub 2023 Jan 26. Nat Immunol. 2023. PMID: 36703005 Free article.
YAP1 is essential for self-organized differentiation of pluripotent stem cells.
Zeevaert K, Goetzke R, Elsafi Mabrouk MH, Schmidt M, Maaßen C, Henneke AC, He C, Gillner A, Zenke M, Wagner W. Zeevaert K, et al. Among authors: zenke m. Biomater Adv. 2023 Mar;146:213308. doi: 10.1016/j.bioadv.2023.213308. Epub 2023 Jan 25. Biomater Adv. 2023. PMID: 36774716 Free article.
Proinflammatory phenotype of iPS cell-derived JAK2 V617F megakaryocytes induces fibrosis in 3D in vitro bone marrow niche.
Flosdorf N, Böhnke J, de Toledo MAS, Lutterbach N, Lerma VG, Graßhoff M, Olschok K, Gupta S, Tharmapalan V, Schmitz S, Götz K, Schüler HM, Maurer A, Sontag S, Küstermann C, Seré K, Wagner W, Costa IG, Brümmendorf TH, Koschmieder S, Chatain N, Castilho M, Schneider RK, Zenke M. Flosdorf N, et al. Among authors: zenke m. Stem Cell Reports. 2024 Feb 13;19(2):224-238. doi: 10.1016/j.stemcr.2023.12.011. Epub 2024 Jan 25. Stem Cell Reports. 2024. PMID: 38278152 Free PMC article.
253 results