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Dupilumab demonstrated efficacy and was well tolerated regardless of prior use of swallowed topical corticosteroids in adolescent and adult patients with eosinophilic oesophagitis: a subgroup analysis of the phase 3 LIBERTY EoE TREET study.
Bredenoord AJ, Dellon ES, Hirano I, Lucendo AJ, Schlag C, Sun X, Glotfelty L, Mannent L, Maloney J, Laws E, Mortensen E, Shabbir A. Bredenoord AJ, et al. Among authors: glotfelty l. Gut. 2024 Feb 23;73(3):398-406. doi: 10.1136/gutjnl-2023-330220. Gut. 2024. PMID: 38050037 Free PMC article. Clinical Trial.
Efficacy and safety of dupilumab up to 52 weeks in adults and adolescents with eosinophilic oesophagitis (LIBERTY EoE TREET study): a multicentre, double-blind, randomised, placebo-controlled, phase 3 trial.
Rothenberg ME, Dellon ES, Collins MH, Hirano I, Chehade M, Bredenoord AJ, Lucendo AJ, Spergel JM, Sun X, Hamilton JD, Mortensen E, Laws E, Maloney J, Mannent LP, McCann E, Liu X, Glotfelty L, Shabbir A. Rothenberg ME, et al. Among authors: glotfelty l. Lancet Gastroenterol Hepatol. 2023 Nov;8(11):990-1004. doi: 10.1016/S2468-1253(23)00204-2. Epub 2023 Aug 31. Lancet Gastroenterol Hepatol. 2023. PMID: 37660704
The enteric nervous system relays psychological stress to intestinal inflammation.
Schneider KM, Blank N, Alvarez Y, Thum K, Lundgren P, Litichevskiy L, Sleeman M, Bahnsen K, Kim J, Kardo S, Patel S, Dohnalová L, Uhr GT, Descamps HC, Kircher S, McSween AM, Ardabili AR, Nemec KM, Jimenez MT, Glotfelty LG, Eisenberg JD, Furth EE, Henao-Mejia J, Bennett FC, Pierik MJ, Romberg-Camps M, Mujagic Z, Prinz M, Schneider CV, Wherry EJ, Bewtra M, Heuckeroth RO, Levy M, Thaiss CA. Schneider KM, et al. Among authors: glotfelty lg. Cell. 2023 Jun 22;186(13):2823-2838.e20. doi: 10.1016/j.cell.2023.05.001. Epub 2023 May 25. Cell. 2023. PMID: 37236193
The Microbiome as a Circadian Coordinator of Metabolism.
Alvarez Y, Glotfelty LG, Blank N, Dohnalová L, Thaiss CA. Alvarez Y, et al. Among authors: glotfelty lg. Endocrinology. 2020 Jun 1;161(6):bqaa059. doi: 10.1210/endocr/bqaa059. Endocrinology. 2020. PMID: 32291454 Free PMC article. Review.