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Inhibition of nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme of the nicotinamide adenine dinucleotide (NAD) salvage pathway, to target glioma heterogeneity through mitochondrial oxidative stress.
Sharma P, Xu J, Williams K, Easley M, Elder JB, Lonser R, Lang FF, Lapalombella R, Sampath D, Puduvalli VK. Sharma P, et al. Among authors: elder jb. Neuro Oncol. 2022 Feb 1;24(2):229-244. doi: 10.1093/neuonc/noab175. Neuro Oncol. 2022. PMID: 34260721 Free PMC article.
Unsupervised machine learning models reveal predictive markers of glioblastoma patient survival using white blood cell counts prior to initiating chemoradiation.
Wang W, Kumm ZT, Ho C, Zanesco-Fontes I, Texiera G, Reis RM, Martinetto H, Khan J, Anderson MD, Chohan MO, Beyer S, Elder JB, Giglio P, Otero JJ. Wang W, et al. Among authors: elder jb. Res Sq [Preprint]. 2023 Apr 21:rs.3.rs-2834239. doi: 10.21203/rs.3.rs-2834239/v1. Res Sq. 2023. PMID: 37131745 Free PMC article. Updated. Preprint.
Unsupervised machine learning models reveal predictive clinical markers of glioblastoma patient survival using white blood cell counts prior to initiating chemoradiation.
Wang W, Kumm ZT, Ho C, Zanesco-Fontes I, Texiera G, Reis RM, Martinetto H, Khan J, McCandless MG, Baker KE, Anderson MD, Chohan MO, Beyer S, Elder JB, Giglio P, Otero JJ. Wang W, et al. Among authors: elder jb. Neurooncol Adv. 2023 Nov 11;6(1):vdad140. doi: 10.1093/noajnl/vdad140. eCollection 2024 Jan-Dec. Neurooncol Adv. 2023. PMID: 38405202 Free PMC article.
Disruption of DNA Repair and Survival Pathways through Heat Shock Protein Inhibition by Onalespib to Sensitize Malignant Gliomas to Chemoradiation Therapy.
Xu J, Wu PJ, Lai TH, Sharma P, Canella A, Welker AM, Beattie CE, Elder JB, Easley M, Lonser R, Jacob NK, Pietrzak M, Timmers CM, Lang F, Sampath D, Puduvalli VK. Xu J, et al. Among authors: elder jb. Clin Cancer Res. 2022 May 2;28(9):1979-1990. doi: 10.1158/1078-0432.CCR-20-0468. Clin Cancer Res. 2022. PMID: 35140124 Free PMC article.
Safety and Feasibility of Stereotactic Radiosurgery for Patients with 15 or more Brain Metastases.
Upadhyay R, Palmer JD, Klamer BG, Perlow HK, Schoenhals JE, Ghose J, Rajappa P, Blakaj DM, Beyer S, Grecula JC, Sim AJ, Lu L, Zoller W, Elder JB, Chakravarti A, Thomas E, Raval RR. Upadhyay R, et al. Among authors: elder jb. Adv Radiat Oncol. 2024 Apr 16;9(7):101509. doi: 10.1016/j.adro.2024.101509. eCollection 2024 Jul. Adv Radiat Oncol. 2024. PMID: 38799108 Free PMC article.
Autologous cell immunotherapy (IGV-001) with IGF-1R antisense oligonucleotide in newly diagnosed glioblastoma patients.
Lee IY, Hanft S, Schulder M, Judy KD, Wong ET, Elder JB, Evans LT, Zuccarello M, Wu J, Aulakh S, Agarwal V, Ramakrishna R, Gill BJ, Quiñones-Hinojosa A, Brennan C, Zacharia BE, Silva Correia CE, Diwanji M, Pennock GK, Scott C, Perez-Olle R, Andrews DW, Boockvar JA. Lee IY, et al. Among authors: elder jb. Future Oncol. 2024 Mar;20(10):579-591. doi: 10.2217/fon-2023-0702. Epub 2023 Dec 7. Future Oncol. 2024. PMID: 38060340
250 results