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Page 1
Protocol and statistical analysis plan for the mega randomised registry trial research program comparing conservative versus liberal oxygenation targets in adults receiving unplanned invasive mechanical ventilation in the ICU (Mega-ROX).
Young PJ, Arabi YM, Bagshaw SM, Bellomo R, Fujii T, Haniffa R, Hodgson CL, Vijayaraghavan BKT, Litton E, Mackle D, Nichol AD, Kasza J; Mega-ROX Management Committee; Australian and New Zealand Intensive Care Society Clinical Trials Group; Crit Care Asia and Africa Network; Irish Critical Care Clinical Trials Group; Alberta Health Services Critical Care Strategic Clinical Network. Young PJ, et al. Among authors: mackle d. Crit Care Resusc. 2023 Oct 19;24(2):137-149. doi: 10.51893/2022.2.OA4. eCollection 2022 Jun 6. Crit Care Resusc. 2023. PMID: 38045600 Free PMC article.
Protocol and statistical analysis plan for the Randomised Evaluation of Active Control of Temperature versus Ordinary Temperature Management (REACTOR) trial.
Young PJ, Bailey MJ, Beasley RW, Freebairn RC, Hammond NE, Haren FM, Harward ML, Henderson SJ, Mackle DM, McArthur CJ, McGuinness SP, Myburgh JA, Saxena MK, Turner A, Webb SA, Bellomo R; The ANZICS Clinical Trials Group. Young PJ, et al. Crit Care Resusc. 2017 Mar;19(1):81-87. Crit Care Resusc. 2017. PMID: 28215136 Clinical Trial.
Intensive care unit randomised trial comparing two approaches to oxygen therapy (ICU-ROX): results of the pilot phase.
Young PJ, Mackle DM, Bailey MJ, Beasley RW, Bennett VL, Deane AM, Eastwood GM, Finfer S, Freebairn RC, Litton E, Linke NJ, McArthur CJ, McGuinness SP, Panwar R, Bellomo R; The ICU-ROX pilot investigators; The Australian and New Zealand Intensive Care Society Clinical Trials Group. Young PJ, et al. Crit Care Resusc. 2017 Dec;19(4):344-354. Crit Care Resusc. 2017. PMID: 29202261 Clinical Trial.
Protocol summary and statistical analysis plan for the intensive care unit randomised trial comparing two approaches to oxygen therapy (ICU-ROX).
Mackle DM, Bailey MJ, Beasley RW, Bellomo R, Bennett VL, Deane AM, Eastwood GM, Finfer S, Freebairn RC, Litton E, Linke NJ, McArthur CJ, McGuinness SP, Panwar R, Young PJ; Australian and New Zealand Intensive Care Society Clinical Trials Group. Mackle DM, et al. Crit Care Resusc. 2018 Mar;20(1):22-32. Crit Care Resusc. 2018. PMID: 29458318 Clinical Trial.
A cluster randomised, crossover, registry-embedded clinical trial of proton pump inhibitors versus histamine-2 receptor blockers for ulcer prophylaxis therapy in the intensive care unit (PEPTIC study): study protocol.
Young PJ, Bagshaw SM, Forbes A, Nichol A, Wright SE, Bellomo R, Bailey MJ, Beasley RW, Eastwood GM, Festa M, Gattas D, van Haren F, Litton E, Mouncey PR, Navarra L, Pilcher D, Mackle DM, McArthur CJ, McGuinness SP, Saxena MK, Webb S, Rowan KM; Australian and New Zealand Intensive Care Society Clinical Trials Group on behalf of the PEPTIC investigators. Young PJ, et al. Among authors: mackle dm. Crit Care Resusc. 2018 Sep;20(3):182-189. Crit Care Resusc. 2018. PMID: 30153780 Clinical Trial.
Protocol summary and statistical analysis plan for the low oxygen intervention for cardiac arrest injury limitation (LOGICAL) trial.
Young PJ, Hodgson CL, Mackle D, Mather AM, Beasley R, Bellomo R, Bernard S, Brickell K, Deane AM, Eastwood G, Finfer S, Higgins AM, Hunt A, Lawrence C, Linke NJ, Litton E, McDonald CF, Moore J, Nichol AD, Olatunji S, Parke RL, Peake S, Secombe P, Seppelt IM, Turner A, Trapani T, Udy A, Kasza J; LOGICAL management committee, the Australian and New Zealand Intensive Care Society Clinical Trials Group, and the Irish Critical Care Trials Group. Young PJ, et al. Among authors: mackle d. Crit Care Resusc. 2023 Jul 26;25(3):140-146. doi: 10.1016/j.ccrj.2023.06.007. eCollection 2023 Sep. Crit Care Resusc. 2023. PMID: 37876368 Free PMC article.
Protocol and statistical analysis plan for the mega randomised registry trial comparing conservative vs. liberal oxygenation targets in adults with sepsis in the intensive care unit (Mega-ROX Sepsis).
Young PJ, Al-Fares A, Aryal D, Arabi YM, Ashraf MS, Bagshaw SM, Beane A, de Oliveira Manoel AL, Dullawe L, Fazla F, Fujii T, Haniffa R, Hodgson CL, Hunt A, Tirupakuzhi Vijayaraghavan BK, Landoni G, Lawrence C, Maia IS, Mackle D, Mazlan MZ, Nichol AD, Olatunji S, Rashan A, Rashan S, Kasza J; Mega-ROX management committee; Australian and New Zealand Intensive Care Society Clinical Trials Group; Critical Care Asia and Africa Network; Irish Critical Care-Clinical Trials Group. Young PJ, et al. Among authors: mackle d. Crit Care Resusc. 2023 May 22;25(2):106-112. doi: 10.1016/j.ccrj.2023.04.008. eCollection 2023 Jun. Crit Care Resusc. 2023. PMID: 37876605 Free PMC article.
Protocol and statistical analysis plan for the mega randomised registry trial comparing conservative vs. liberal oxygenation targets in adults with nonhypoxic ischaemic acute brain injuries and conditions in the intensive care unit (Mega-ROX Brains).
Young PJ, Al-Fares A, Aryal D, Arabi YM, Ashraf MS, Bagshaw SM, Mat-Nor MB, Beane A, Borghi G, de Oliveira Manoel AL, Dullawe L, Fazla F, Fujii T, Haniffa R, Hodgson CL, Hunt A, Lawrence C, Mackle D, Mangal K, Nichol AD, Olatunji S, Rashan A, Rashan S, Tomazini B, Kasza J; Mega-ROX management committee; Australian and New Zealand Intensive Care Society Clinical Trials Group; Brazilian Research in Intensive Care Network; Critical Care Asia and Africa Network; Irish Critical Care-Clinical Trials Group. Young PJ, et al. Among authors: mackle d. Crit Care Resusc. 2023 May 20;25(1):53-59. doi: 10.1016/j.ccrj.2023.04.011. eCollection 2023 Mar. Crit Care Resusc. 2023. PMID: 37876994 Free PMC article.
The Plasma-Lyte 148 versus Saline (PLUS) statistical analysis plan: a multicentre, randomised controlled trial of the effect of intensive care fluid therapy on mortality.
Billot L, Bellomo R, Gallagher M, Gattas D, Hammond NE, Mackle D, Micallef S, Myburgh J, Navarra L, Saxena M, Taylor C, Young PJ, Finfer S; PLUS Study investigators and the ANZICS Clinical Trials Group. Billot L, et al. Among authors: mackle d. Crit Care Resusc. 2023 Oct 18;23(1):24-31. doi: 10.51893/2021.1.OA2. eCollection 2021 Mar. Crit Care Resusc. 2023. PMID: 38046395 Free PMC article.
83 results