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Aryl hydrocarbon receptor is a tumor promoter in MYCN-amplified neuroblastoma cells through suppression of differentiation.
Chaudhry KA, Jacobi JJ, Gillard BM, Karasik E, Martin JC, da Silva Fernandes T, Hurley E, Feltri ML, Attwood KM, Twist CJ, Smiraglia DJ, Long MD, Bianchi-Smiraglia A. Chaudhry KA, et al. Among authors: attwood km. iScience. 2023 Oct 21;26(11):108303. doi: 10.1016/j.isci.2023.108303. eCollection 2023 Nov 17. iScience. 2023. PMID: 38026169 Free PMC article.
GRM1 is An Androgen-Regulated Gene and its Expression Correlates with Prostate Cancer Progression in Pre-Clinical Models.
Shourideh M, Azabdaftari G, Attwood K, DePriest A, Wadosky KM, Gillard BM, Karasik E, Heemers H, Kyprianou N, Gelman IH, Corey E, Vessella RL, Mohler JL, Koochekpour S. Shourideh M, et al. Among authors: attwood k. Clin Cancer Res. 2016 Jul 25:clincanres.0137.2016. doi: 10.1158/1078-0432.CCR-16-0137. Online ahead of print. Clin Cancer Res. 2016. PMID: 27458247 Retracted.
Pharmacological polyamine catabolism upregulation with methionine salvage pathway inhibition as an effective prostate cancer therapy.
Affronti HC, Rowsam AM, Pellerite AJ, Rosario SR, Long MD, Jacobi JJ, Bianchi-Smiraglia A, Boerlin CS, Gillard BM, Karasik E, Foster BA, Moser M, Wilton JH, Attwood K, Nikiforov MA, Azabdaftari G, Pili R, Phillips JG, Casero RA Jr, Smiraglia DJ. Affronti HC, et al. Nat Commun. 2020 Jan 7;11(1):52. doi: 10.1038/s41467-019-13950-4. Nat Commun. 2020. PMID: 31911608 Free PMC article.
A synergistic two-drug therapy specifically targets a DNA repair dysregulation that occurs in p53-deficient colorectal and pancreatic cancers.
Alruwaili MM, Zonneville J, Naranjo MN, Serio H, Melendy T, Straubinger RM, Gillard B, Foster BA, Rajan P, Attwood K, Chatley S, Iyer R, Fountzilas C, Bakin AV. Alruwaili MM, et al. Cell Rep Med. 2024 Mar 19;5(3):101434. doi: 10.1016/j.xcrm.2024.101434. Epub 2024 Feb 21. Cell Rep Med. 2024. PMID: 38387463 Free PMC article.
Facilitates chromatin transcription complex is an "accelerator" of tumor transformation and potential marker and target of aggressive cancers.
Garcia H, Miecznikowski JC, Safina A, Commane M, Ruusulehto A, Kilpinen S, Leach RW, Attwood K, Li Y, Degan S, Omilian AR, Guryanova O, Papantonopoulou O, Wang J, Buck M, Liu S, Morrison C, Gurova KV. Garcia H, et al. Cell Rep. 2013 Jul 11;4(1):159-73. doi: 10.1016/j.celrep.2013.06.013. Epub 2013 Jul 3. Cell Rep. 2013. PMID: 23831030 Free PMC article.
248 results